YIKE_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YIKE_SCHPO
• UniProt AC: Q8TFH0
• Protein Name: Probable 6-phosphofructo-2-kinase PB17E12.14c
• Gene Name: SPAPB17E12.14c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 668
• Protein Description: Synthesis of fructose 2,6-bisphosphate..
• Protein Sequence: MSNNNNKDDSELQSRTHYYNPDRTAIPVKDDVDQLDKFGSPKLSANDHSFTNTDSVTSEDRPFSSPVSTLTSNSANFSDSSLQNSPVHPIPSPALSPTLNLGSRPDVKRVSSGGYFALPKQLTSIRQTHRPMSQQHRVPSFHPASDTAPPSPIPFHHHLRKKGSSMSIPGQTSIVSSNNGSEATNPPEEKLAIIMVGLPARGKSYIVNKLVRYYNWLQYNCKAFNVGNFRRKHASHSHDDASFFDPSNEEASKLRESFAMDTLDALLQWFEEEDGVVGIFDATNSTSKRRKAIVDHLSKVPYVTTLFIESICNDEQLIAANMRMKLVGPDYKDLNPEQSLRDFQERVRMYERKYEPLGKSEEDLNLRYIKVINVGKKVVAFNIRGFLAGQAVFFLLNFNLSPRQIWVTRHGESVDNVRGRIGGNAELTPLGRQFSEDLALFIDEKRDEFQERLYNDYSKESHLLQHGSHSFNGKQFETSFNCLTPSENTVNDPQVLDPEDEERLEKPYSVWTSMMQRSIQTAAYFDEEQYDIKAMRMLNEICSGICDGLTYEEIKSIYPKEYEARKLDKLNYRYPGSGGESYLDVIYRLQSVIVEIERMKHHVLVIGHRVITRIIIAYFLGCRREDIAYLNVPLHTVYCIEPQPYGTDFYQYNYDPNTRKFSRVPFSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	DQLDKFGSPKLSAND HHHHHCCCCCCCCCC	23.22	25720772
111	Phosphorylation	RPDVKRVSSGGYFAL CCCCEEECCCCCCCC	27.57	25720772
112	Phosphorylation	PDVKRVSSGGYFALP CCCEEECCCCCCCCC	33.12	24763107
115	Phosphorylation	KRVSSGGYFALPKQL EEECCCCCCCCCHHH	6.82	25720772
145	Phosphorylation	VPSFHPASDTAPPSP CCCCCCCCCCCCCCC	39.69	29996109
147	Phosphorylation	SFHPASDTAPPSPIP CCCCCCCCCCCCCCC	38.27	29996109
151	Phosphorylation	ASDTAPPSPIPFHHH CCCCCCCCCCCCCCC	34.11	29996109
164	Phosphorylation	HHLRKKGSSMSIPGQ CCHHCCCCCCCCCCC	31.57	25720772
165	Phosphorylation	HLRKKGSSMSIPGQT CHHCCCCCCCCCCCC	25.80	25720772
167	Phosphorylation	RKKGSSMSIPGQTSI HCCCCCCCCCCCCEE	27.81	24763107
204	Phosphorylation	GLPARGKSYIVNKLV CCCCCCCHHHHHHHH	23.94	19547744
205	Phosphorylation	LPARGKSYIVNKLVR CCCCCCHHHHHHHHH	16.63	19547744

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YIKE_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YIKE_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YIKE_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YIKE_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.