YI001_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YI001_HUMAN
• UniProt AC: Q96NJ1
• Protein Name: Uncharacterized protein FLJ30774
• Organism: Homo sapiens (Human).
• Sequence Length: 140
• Protein Sequence: MRRERPELRDAEGRLRLRAGCLVTAWPRAPSGAGSWSMAAASPWPASWGFPDASSTVPSLCTEARAGRGGPATARSRVSADSQGGRAGSSSPSSALRLCCAGPSQAHPGPSPAVLPGRCGLLGSFPRPPAPQGRWGPSLG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
73	Phosphorylation	AGRGGPATARSRVSA CCCCCCCCHHHHCCC	26.24	17525332
79	Phosphorylation	ATARSRVSADSQGGR CCHHHHCCCCCCCCC	25.83	-
82	Phosphorylation	RSRVSADSQGGRAGS HHHCCCCCCCCCCCC	30.37	17525332
90	Phosphorylation	QGGRAGSSSPSSALR CCCCCCCCCHHHHHH	45.40	-
138	Phosphorylation	PQGRWGPSLG----- CCCCCCCCCC-----	41.61	19690332

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YI001_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YI001_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YI001_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of YI001_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-138, AND MASSSPECTROMETRY.
PubMed: 19690332

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-73 AND SER-82, AND MASSSPECTROMETRY.
PubMed: 17525332