YHV3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YHV3_SCHPO
• UniProt AC: Q9P7R8
• Protein Name: Uncharacterized protein C211.03
• Gene Name: SPBC211.03c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 1462
• Subcellular Localization: Cytoplasm . Golgi apparatus membrane ; Single-pass membrane protein .
• Protein Sequence: MEVPRASPNQEPLCSISPSSLVINEIITVVTAIRKTTRWRNSGVASILGVSTLKDEFLADGLESRWKTNGEKSSSIRYPLVMEFSQLKEDLTNRASLNGYDSLKLLSPFLRTIKSPRMTGYITSLCLSAILKFFSFRIISEESPNLALSMRNLSFAITQCRFESFDASQDEAVLLRVSRLMEELLRGPGKAVLSDDSICEIVETGLSMCCQSRLSQVLRYSAELSMTSILEKIFERLKYIDVKTDSEDFWDASEEHSIKGEEFHYKKITEGDEISNEIDPFGIGSIREVFRVLVSFIDFGKQKFSDNIKAMALRFINTALEVSGSHISDFPSLRVLITDTLCKSLLQLIRSDHTALLTNSLLVMTTLLQAMPGSLKLQQELFISYLISCLHIPSTTPRERNVETSLHKVVSSLDLSEEISPDRATPTSFTERKRFAFDTRNRPPEVRELIVECLGSLSRIPYFLIDLYVNYDCDPQMSDLAIDLLKVLTRNCLVDSARYSTANVPPLCLDALLNFIYYFHEHLQPCYNDPNNTFKDDVAKTLIESKKRKAIIIEGAELFNESPSDGIAFLTQHSIIKQSDNPTCIVEFFHSTNRLSKRVLGEFLTKGSNSHILNAFISAFDFKGKRIDEALRLLLQSFRLPGESQLIERVLETFSHYYMSANPDSMSSKDAAFVLSYSIIMLNTDQHNPNIKSQRRMTLDDFCRNVRGVNDGQDFDRNFLSEIYKAIKENEIIVAEEHDTELSFLYIWSKLQQSVKITEPFKRSSSNVHDKIVFLEVWKSIMAALIYVFSTATEDTVFYRVVNGIQQATEVAAAYELNEPVDYAIERFCQFTALDPSSVPGTQLNTAIKVEDRIITVSELSVRFGRDFRAQLALLVLFWISSKFGNIIDASWPLLVQLTICLARNNLIDNSFLPGFKLFGYQWFPFPEPPLNSGKPALSKEGGLLSALSSYLSSYANDEPPCPTDEEIQHTLCTIDCISSAKIDNFLTKLVDLKQPGLNKLLDSLLSLSNPSTSLLTDENTVDDNKVSSVEALSNIQSAIVADLLTSLFLGTRESLNKLERRTQILSYLLFQIEQSGDEKVINQLSLYIFEMFMDDDLKLSENSEDWGLFSKLCNLLNDKNIVVRNQSLSLFHQLVNKYPFLLESWIGLQLVQSAVNTNTADIDDLYRLLSKIPTNLLDLPMFQVYLGCVDTLIQTIVKQIAQILSKQKKGASKGLPFDKSILDNHSAELNDAFNLFLKAAVEYKVDSNESSEHFQDTRWKIIYDHVCKLCLSRSRSLRAASLSCLQRIVVEQLDQPHEVSYTMALFHLVLLPTMENMITVLTEKPEHKIFGLAQAQMFNIICKTVLIDMNVLSAQKEMLHTLWLKLMDVAIKLSSIHGSESMAEVMESIKNVFMILHGAGALAGPTIEVDPEIPDHLIKTWNTTWNNLFIYYPELSNDLNINNEAEMKKENLKNPSQTTTV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Phosphorylation	WRNSGVASILGVSTL CCCCCHHHHCCCCCC	18.88	25720772
96	Phosphorylation	EDLTNRASLNGYDSL HHHCCCHHHCCHHHH	21.09	21712547
100	Phosphorylation	NRASLNGYDSLKLLS CCHHHCCHHHHHHHH	10.98	21712547
102	Phosphorylation	ASLNGYDSLKLLSPF HHHCCHHHHHHHHHH	20.94	21712547
411	Phosphorylation	TSLHKVVSSLDLSEE HHHHHHHHCCCCCCC	28.33	28889911
412	Phosphorylation	SLHKVVSSLDLSEEI HHHHHHHCCCCCCCC	17.81	25720772
416	Phosphorylation	VVSSLDLSEEISPDR HHHCCCCCCCCCCCC	32.61	21712547
420	Phosphorylation	LDLSEEISPDRATPT CCCCCCCCCCCCCCC	24.83	28889911
425	Phosphorylation	EISPDRATPTSFTER CCCCCCCCCCCCHHH	28.17	25720772
427	Phosphorylation	SPDRATPTSFTERKR CCCCCCCCCCHHHHH	31.92	24763107
428	Phosphorylation	PDRATPTSFTERKRF CCCCCCCCCHHHHHH	31.23	29996109
430	Phosphorylation	RATPTSFTERKRFAF CCCCCCCHHHHHHCC	34.35	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YHV3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YHV3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YHV3_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YHV3_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-411 AND SER-420, ANDMASS SPECTROMETRY.
PubMed: 18257517