YFN1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YFN1_SCHPO
• UniProt AC: Q1MTM9
• Protein Name: Uncharacterized transcriptional regulatory protein C1327.01c
• Gene Name: SPAC1327.01c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 977
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Sequence: MMQQRSGSLSLLSNAVQAGQSSDPMQDDPAKTEPGTPKGYDGSKNSSPASVPSWIHEKTKAGKDRKRLPLACQSCRKKKVKCSGERPSCDQCLKHNIPCIYKSNSTKRSHSRHEEIHHQQQLHLNHQYQHQHKNVAANSIDNLSRQYSQPNHINTHDSVNSPPSYGIMASATNQPLSHPTIVPSSNSSSLLNSTNNISHNPQVSLMSASLSKNLVLDPASPKSVSPDLVYVSSDNPPVSTAASAYSSSLPISDVTRALPLAPASNSQHPSLSSQPVSVPSNTINIPTDSLSIVSNPSQTPAKFDSNRISQVPNSDYSIYSNFNNFPIANHAPSFPQSSVKKLDSSFSPTSLPTFTTNSASSGLSTSYTNNNDTTSDNNSLQAVPRLDPVPSLTLSSTPVAELPPLELRIHLAEVFFHCCHGQSYNLFHRPTFFESLNNNTVPLVVVYAVCAVSARFSSRMHDRFSPPYMAGEQYAREARRLALDNFDRPDLSLVAALLLLSLHDSGTCETGKSWMYGGMALRMAAALQLNCEQGSNPLDLDNIDSGPRISFLERELRRRTFWSCFLMDRYASSHEHLQFLDENDIGIQLPVHELLFTKQIAGVTQTLDGRILEGVPSIVIPADTTENMGVAAYTVKIIALWGRAVKYLKQDGKRRDPYPYWHRNSDFSHISEALYAWADGLPQRLKYSAVGLENHLSIQQGAQYAFLHLAYHHTLMWLFRSIGETENNQLSKISSSVSLAGNTVSFSPVSHTPINVTNGESQNNSNNDPSANGAARRLHKAAREICLRCANAISMIVDDCRKHNVILTSPFIASGVYTAFCVQAEAAFGSNVLAASTARHNLEIDLRLMLEMKNYWGSISALCDKMSEIWADWVQRTSSGIQEEDTIPNEMIDEERMLDLEKHFMYITESPIVPNQAAQKSYSPDLMSYFGFAKNSDLQQWNGLWPSDDLRNYQESTIDSLVAYATGNPGWNISFAG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MMQQRSGSLSLLS --CCCCCCCHHHHHH	28.53	25720772
36	Phosphorylation	PAKTEPGTPKGYDGS CCCCCCCCCCCCCCC	32.32	29996109
43	Phosphorylation	TPKGYDGSKNSSPAS CCCCCCCCCCCCCCC	26.26	25720772
46	Phosphorylation	GYDGSKNSSPASVPS CCCCCCCCCCCCCCH	41.24	25720772
47	Phosphorylation	YDGSKNSSPASVPSW CCCCCCCCCCCCCHH	33.60	21712547
50	Phosphorylation	SKNSSPASVPSWIHE CCCCCCCCCCHHHHH	37.63	21712547
53	Phosphorylation	SSPASVPSWIHEKTK CCCCCCCHHHHHHCC	36.18	21712547
139	Phosphorylation	HKNVAANSIDNLSRQ HCCHHHHHHHHHHHH	26.96	25720772
220	Phosphorylation	NLVLDPASPKSVSPD CCCCCCCCCCCCCCC	37.94	28889911
223	Phosphorylation	LDPASPKSVSPDLVY CCCCCCCCCCCCEEE	31.07	25720772
225	Phosphorylation	PASPKSVSPDLVYVS CCCCCCCCCCEEEEC	21.56	25720772
921	Phosphorylation	PNQAAQKSYSPDLMS CCHHHHHCCCCCHHH	20.82	29996109
923	Phosphorylation	QAAQKSYSPDLMSYF HHHHHCCCCCHHHHH	21.01	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YFN1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YFN1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YFN1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CAP_SCHPO	cap1	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-220, AND MASSSPECTROMETRY.
PubMed: 18257517