dbPTM

YDU2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YDU2_SCHPO
UniProt AC	O13863
Protein Name	Uncharacterized kinase C1B1.02c
Gene Name	SPAC1B1.02c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	537
Subcellular Localization
Protein Description
Protein Sequence	MEPGSKLSEDETFSQTFNEEEQEDSRNKDILAFDPSVDNEPLLTKKLSSLSIYSEPSPDEASNLQELKFVSSPPSVRVPRSRRNRRNSRVDSEARKRQFDRVKHSVSNSCKLHLSLQGQEAAQLRSDSLYLEASDKRDLTSLVTRVKELARKLSAARLAFRFRKVLLICNDNKESIERSVELAQWLLDTFSFTPSSSHNNMASSNTQSNTQLSEMESEEKSFNKDVYPNDEYTPFTPKNQFVIYLEDTLASLDVVESLSPKKNVRFWTSELCTQCPNLFDCVITVGDDSAALRASWLFQDVVPPVLSFSTAKAGFLSILPIAEYTKTLDLIFHRGFTVNLRMRFQCSIMRYVGEHSTHICEGQYSVLNELLIDRGPNPFMISLDLYVENEYITTLQSDGVCVSTPTGSTAYSVAAGGSLCHPGIPAILISAICPHSLSFRPIILPDSMTLRIVVPLDARSNAWCAFDGHHRIELGLGDYISISASSFPFPSVIRSKYSKDWFDILRQTLNWNDRKGRQRSSRYKSHVHKTNTSEEQN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MEPGSKLSEDET ---CCCCCCCCCCCC	40.93	21712547
12	Phosphorylation	SKLSEDETFSQTFNE CCCCCCCCHHHHCCH	40.69	24763107
36	Phosphorylation	DILAFDPSVDNEPLL CEEEECCCCCCCCHH	43.90	21712547
48	Phosphorylation	PLLTKKLSSLSIYSE CHHHHCHHHCEECCC	37.81	24763107
49	Phosphorylation	LLTKKLSSLSIYSEP HHHHCHHHCEECCCC	36.25	24763107
51	Phosphorylation	TKKLSSLSIYSEPSP HHCHHHCEECCCCCC	22.79	21712547
53	Phosphorylation	KLSSLSIYSEPSPDE CHHHCEECCCCCCCC	12.01	21712547
54	Phosphorylation	LSSLSIYSEPSPDEA HHHCEECCCCCCCCC	41.16	24763107
57	Phosphorylation	LSIYSEPSPDEASNL CEECCCCCCCCCCCC	40.71	28889911
71	Phosphorylation	LQELKFVSSPPSVRV CHHEEECCCCCCCCC	40.01	29996109
72	Phosphorylation	QELKFVSSPPSVRVP HHEEECCCCCCCCCC	35.21	28889911
75	Phosphorylation	KFVSSPPSVRVPRSR EECCCCCCCCCCCCH	26.41	25720772
88	Phosphorylation	SRRNRRNSRVDSEAR CHHCCCCCCCCHHHH	31.69	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YDU2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YDU2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YDU2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YDU2_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YDU2_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-72, AND MASSSPECTROMETRY.	18257517 [Abstract]