dbPTM

YDM6_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YDM6_SCHPO
UniProt AC	P87137
Protein Name	Uncharacterized protein C57A7.06
Gene Name	SPAC57A7.06
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	929
Subcellular Localization	Nucleus, nucleolus .
Protein Description
Protein Sequence	MARKGKVNTLPQPQGKHQRKGKKQLENKILHSYEEESAGFDSEELEDNDEQGYSFGVNSEDDEEIDSDEAFDEEDEKRFADWSFNASKSGKSNKDHKNLNNTKEISLNEEDDSDDSVNSDKLENEGSVGSSIDENELVDLDTLLDNDQPEKNESNTASTIRPPWIGNNDHATDKENLLESDASSSNDSESELTDSADNMNESDSESEIESSDSDHDDGENSDSKLDNLRNYIVSLNQKRKKDEADAESVLSSDDNDSIEEISIKKVKYDPHETNKESEYNLIGSSEKTIDITDLLDSIPMNEQLKVSLKPLVSESSSISSKKLDAPLAKSIQDRLERQAAYEQTKNDLEKWKPIVADNRKSDQLIFPMNETARPVPSNNGLASSFEPRTESERKMHQALLDAGLENESALKKQEELALNKLSVEEVAERTRQLRFMRELMFREERKAKRVAKIKSKTYRKIRKNRKEKEMALIPKSEEDLENERIKSEEARALERMTQRHKNTSSWTRKMLERASHGEGTREAVNEQIRKGDELMQRIHGKEISEMDGEDVSEFSDSDYDTNEQVSTAFEKIRNEEEPKLKGVLGMKFMRDASNRQKALVQDEMQAFEDELAGVPNEDDTSQKGEDGVPGVLIGNNTGRRSFKPSEEAAKLSLPSRKNPFVSDSAVLKVNKPEMKEGQKKAEARKKKESPLEATEETNPWLQVPDQRTSSAKKLDKNSSKADKKNHKLKMDKVASLQELVEEPKVQPDLIFEEKAFESASEAESDVDVSVPMLKPTKGRLSIKQRELVAKAFAGDDVVAEFEKDKEDWVQEDAPKEEDHSLPGWGSWGGVGVKQRKTKPKVKKIAGLDPSKRKDSKLKHVIINEKRNKKAAKLTADSVPFPFESREQYERSLNLPMGPEWTTRASHHKAVAPRVVTKRGKVINPIKAPN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
83	Phosphorylation	EKRFADWSFNASKSG HHHHHHHCCCCCCCC	14.79	21712547
251	Phosphorylation	ADAESVLSSDDNDSI HHHHHHHCCCCCCCC	29.57	28889911
252	Phosphorylation	DAESVLSSDDNDSIE HHHHHHCCCCCCCCE	44.84	24763107
257	Phosphorylation	LSSDDNDSIEEISIK HCCCCCCCCEEEEEE	37.85	24763107
476	Phosphorylation	EMALIPKSEEDLENE HHCCCCCCHHHHHHH	40.64	24763107
552	Phosphorylation	EMDGEDVSEFSDSDY HCCCCCHHHCCCCCC	45.29	21712547
555	Phosphorylation	GEDVSEFSDSDYDTN CCCHHHCCCCCCCCH	31.95	28889911
557	Phosphorylation	DVSEFSDSDYDTNEQ CHHHCCCCCCCCHHH	36.55	28889911
620	Phosphorylation	GVPNEDDTSQKGEDG CCCCCCCCCCCCCCC	45.43	21712547
621	Phosphorylation	VPNEDDTSQKGEDGV CCCCCCCCCCCCCCC	36.57	21712547
689	Phosphorylation	EARKKKESPLEATEE HHHHHCCCCCCCCCC	43.60	21712547
708	Phosphorylation	LQVPDQRTSSAKKLD CCCCCCCCCCCHHHC	22.77	21712547
710	Phosphorylation	VPDQRTSSAKKLDKN CCCCCCCCCHHHCCC	43.42	21712547
758	Phosphorylation	FEEKAFESASEAESD CCHHHHCCHHHHHCC	30.55	28889911
760	Phosphorylation	EKAFESASEAESDVD HHHHCCHHHHHCCCC	46.77	28889911
764	Phosphorylation	ESASEAESDVDVSVP CCHHHHHCCCCCCCC	50.40	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YDM6_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YDM6_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YDM6_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YDM6_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YDM6_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-251; SER-555; SER-557;SER-758; SER-760 AND SER-764, AND MASS SPECTROMETRY.	18257517 [Abstract]