dbPTM

YDD3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YDD3_SCHPO
UniProt AC	O14206
Protein Name	Brix domain-containing protein C1B9.03c
Gene Name	SPAC1B9.03c, SPAC6B12.01
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	389
Subcellular Localization
Protein Description
Protein Sequence	MGGIGKKRVKKRTHLKADPIQEAAIPKSMVIRSGASEVGRSLSLLTRDLRHMMEPHTAIRLKERKANKIKDYLTMAGPLGVTHLLVLSRTDNNANLRIIRAPRGPSLHFRIHEYMLNKDVRRLQKNPKSPTTEFLTPPLLVMNHFNQNSSKDSPHEALLTTTFQNMFPPISVQHTNINSVKRVLLLNRRDDGYIDLRHFIISTKPVGISRPIRHLLKGEKKDSDIPDLHNVRDISDYVLHGDGISGAASDSEIEEDATVEIDRPVPTKTEENLLSASQLLKPKQQAIKLIEIGPRMTLELIKITEDAMGGKVLYHSHVHKSKEEIKQQDNFHEQSRALKEKRKKEQDENVRRKRENKKRRKDQKKEGITSSNKNDDSGNEGSSAYSDTE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Phosphorylation	SEVGRSLSLLTRDLR HHHHHHHHHHHHHHH	23.68	25720772
245	Phosphorylation	VLHGDGISGAASDSE EECCCCCCCCCCCCC	28.10	21712547
249	Phosphorylation	DGISGAASDSEIEED CCCCCCCCCCCCCCC	40.93	21712547
251	Phosphorylation	ISGAASDSEIEEDAT CCCCCCCCCCCCCCE	37.67	29996109
277	Phosphorylation	EENLLSASQLLKPKQ HHHHCCHHHHCCHHH	20.27	21712547
377	Phosphorylation	SSNKNDDSGNEGSSA CCCCCCCCCCCCCCC	46.51	28889911
382	Phosphorylation	DDSGNEGSSAYSDTE CCCCCCCCCCCCCCC	12.96	25720772
383	Phosphorylation	DSGNEGSSAYSDTE- CCCCCCCCCCCCCC-	41.92	25720772
385	Phosphorylation	GNEGSSAYSDTE--- CCCCCCCCCCCC---	14.72	25720772
386	Phosphorylation	NEGSSAYSDTE---- CCCCCCCCCCC----	37.46	25720772
388	Phosphorylation	GSSAYSDTE------ CCCCCCCCC------	37.34	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YDD3_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YDD3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YDD3_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YDD3_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YDD3_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-377, AND MASSSPECTROMETRY.	18257517 [Abstract]