YD22B_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YD22B_YEAST
• UniProt AC: Q03494
• Protein Name: Transposon Ty2-DR2 Gag-Pol polyprotein
• Gene Name: TY2B-DR2
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 1770
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity).; The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP.; Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends (By similarity).; Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity)..
• Protein Sequence: MESQQLHQNPHSQHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQEETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTKVRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYSDILTVLCKSVSKMQTNNQELKDWIALANLEYNGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNSDHINESTVSSQYLSDDNELSLGQQQKESKPTRTIDSNDELPDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQNNQTKLDQFDYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSLNPLQLDKEPVQKVRAPKEVDADISEYNILPSTIRSRTPHIINKESTEMGGTIESDTTSPRHSSTFTARNQKRPGSPNDMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSESTTPIISIETKAVCDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHKSPTDTSDVAKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGEGDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MESQQLHQNP -----CCCCCCCCCC	34.78	28889911
16	Phosphorylation	NPHSQHGSAYASVTS CCCCCCCCEEEEEEC	18.91	30377154
18	Phosphorylation	HSQHGSAYASVTSKE CCCCCCEEEEEECCC	10.91	30377154
20	Phosphorylation	QHGSAYASVTSKEVP CCCCEEEEEECCCCC	17.16	30377154
22	Phosphorylation	GSAYASVTSKEVPSN CCEEEEEECCCCCCC	31.42	30377154
28	Phosphorylation	VTSKEVPSNQDPLAV EECCCCCCCCCCCCE	52.91	22369663
36	Phosphorylation	NQDPLAVSASNLPEF CCCCCCEECCCCCCC	22.00	22369663
38	Phosphorylation	DPLAVSASNLPEFDR CCCCEECCCCCCCCC	31.24	22369663
47	Phosphorylation	LPEFDRDSTKVNSQE CCCCCCCCCCCCCCC	30.90	22369663
48	Phosphorylation	PEFDRDSTKVNSQEE CCCCCCCCCCCCCCC	43.21	22369663
92	Phosphorylation	YQQHGMMTPNKAMAS CCCCCCCCCCHHHHC	18.15	18407956
115	Phosphorylation	SMMTCSHYQTSPAYY CCCCCCCCCCCCCCC	9.37	18407956
117	Phosphorylation	MTCSHYQTSPAYYQP CCCCCCCCCCCCCCC	29.52	18407956
118	Phosphorylation	TCSHYQTSPAYYQPD CCCCCCCCCCCCCCC	7.63	18407956
140	Phosphorylation	YIPPLSTSSPDPIDS CCCCCCCCCCCCCCC	36.18	28889911
141	Phosphorylation	IPPLSTSSPDPIDSQ CCCCCCCCCCCCCCC	33.15	28889911
152	Phosphorylation	IDSQDQHSEVPQAKT CCCCCCCCCCCHHHH	34.36	28889911
182	Ubiquitination	ENFSTWVKFYIRFLK CCHHHHHHHHHHHHH	24.82	17644757
189	Ubiquitination	KFYIRFLKNSNLGDI HHHHHHHHCCCCCCC	56.47	17644757
205	Ubiquitination	PNDQGEIKRQMTYEE CCCCCHHHCCCCHHH	32.07	17644757
209	Phosphorylation	GEIKRQMTYEEHAYI CHHHCCCCHHHHHHH	21.31	30377154
210	Phosphorylation	EIKRQMTYEEHAYIY HHHCCCCHHHHHHHH	17.61	30377154
215	Phosphorylation	MTYEEHAYIYNTFQA CCHHHHHHHHHHHHH	13.07	30377154
217	Phosphorylation	YEEHAYIYNTFQAFA HHHHHHHHHHHHHHC	8.75	30377154
219	Phosphorylation	EHAYIYNTFQAFAPF HHHHHHHHHHHHCCH	10.51	30377154
234	Ubiquitination	HLLPTWVKQILEINY HHHHHHHHHHHHCCH	24.15	17644757
250	Ubiquitination	DILTVLCKSVSKMQT HHHHHHHHHHHHCCC	50.13	17644757
294	Ubiquitination	STIIQRLKENNINVS HHHHHHHHHCCCCHH	61.66	17644757
311	Ubiquitination	LACQLILKGLSGDFK HHHHHHHHHHHCCHH	51.30	17644757
331	Ubiquitination	YRTKTNMKLSQLFAE HHHHHCCCHHHHHHH	47.24	17644757
347	Ubiquitination	QLIYDENKIMNLNKP HHHCCCCCCCCCCCH	41.08	17644757
353	Ubiquitination	NKIMNLNKPSQYKQH CCCCCCCCHHHCCCC	49.57	17644757
355	Phosphorylation	IMNLNKPSQYKQHSE CCCCCCHHHCCCCCC	47.99	21551504
358	Ubiquitination	LNKPSQYKQHSEYKN CCCHHHCCCCCCCCC	33.62	17644757
367	Phosphorylation	HSEYKNVSRTSPNTT CCCCCCCCCCCCCCC	38.95	22369663
369	Phosphorylation	EYKNVSRTSPNTTNT CCCCCCCCCCCCCCC	40.82	22369663
370	Phosphorylation	YKNVSRTSPNTTNTK CCCCCCCCCCCCCCC	18.29	22369663
373	Phosphorylation	VSRTSPNTTNTKVTT CCCCCCCCCCCCEEE	25.47	22369663
374	Phosphorylation	SRTSPNTTNTKVTTR CCCCCCCCCCCEEEC	47.75	22369663
376	Phosphorylation	TSPNTTNTKVTTRNY CCCCCCCCCEEECCC	25.46	22369663
377	Ubiquitination	SPNTTNTKVTTRNYH CCCCCCCCEEECCCC	39.39	22817900
379	Phosphorylation	NTTNTKVTTRNYHRT CCCCCCEEECCCCCC	22.92	27017623
380	Phosphorylation	TTNTKVTTRNYHRTN CCCCCEEECCCCCCC	21.65	17287358
383	Phosphorylation	TKVTTRNYHRTNSSK CCEEECCCCCCCCCC	6.87	27017623
388	Phosphorylation	RNYHRTNSSKPRAAK CCCCCCCCCCCCHHH	38.84	17287358
404	Ubiquitination	HNIATSSKFSRVNSD CCCCCCCCCCCCCCC	47.31	23749301
419	Phosphorylation	HINESTVSSQYLSDD CCCCCCCCCCCCCCC	16.29	28889911
422	Phosphorylation	ESTVSSQYLSDDNEL CCCCCCCCCCCCCCC	15.32	28889911
424	Phosphorylation	TVSSQYLSDDNELSL CCCCCCCCCCCCCCH	37.67	22369663
446	Phosphorylation	KPTRTIDSNDELPDH CCCCCCCCCCCCCCE	42.18	19779198
487	Ubiquitination	INIVDAQKQDIPINA CCEEEHHHCCCCCCC	52.22	23749301
511	Ubiquitination	NGTKTSIKALHTPNI CCCCCEEEEECCCCH	44.66	17644757
555	Ubiquitination	TVLAPIVKHGDFYWL EEEECEEECCCEEEE	42.46	17644757
564	Ubiquitination	GDFYWLSKKYLIPSH CCEEEEECCCCCCHH	43.18	17644757
565	Ubiquitination	DFYWLSKKYLIPSHI CEEEEECCCCCCHHH	41.74	17644757
570	Phosphorylation	SKKYLIPSHISKLTI ECCCCCCHHHHHCEE	26.85	28889911
574	Ubiquitination	LIPSHISKLTINNVN CCCHHHHHCEECCCC	49.39	17644757
582	Ubiquitination	LTINNVNKSKSVNKY CEECCCCCCCCCCCC	55.78	17644757
584	Ubiquitination	INNVNKSKSVNKYPY ECCCCCCCCCCCCCH	61.09	17644757
588	Ubiquitination	NKSKSVNKYPYPLIH CCCCCCCCCCHHHHH	45.51	17644757
612	Ubiquitination	SIQKSLKKNAVTYLK HHHHHHHHCCEEEEE	56.27	15699485
619	Ubiquitination	KNAVTYLKESDIEWS HCCEEEEEHHHCCCC	44.77	17644757
621	Phosphorylation	AVTYLKESDIEWSNA CEEEEEHHHCCCCCC	42.15	21440633
640	Ubiquitination	CPDCLIGKSTKHRHV CCCCCCCCCCCCCCC	48.21	17644757
653	Ubiquitination	HVKGSRLKYQESYEP CCCCCCCCHHHCCCC	43.72	17644757
677	Ubiquitination	GPVHHLPKSAPSYFI CCCCCCCCCCCCEEE	66.66	17644757
690	Ubiquitination	FISFTDEKTRFQWVY EEEEECCCCCEEEEE	48.05	17644757
773	Phosphorylation	VAERLNRTLLNDCRT HHHHHHHHHHHHHHH	34.23	19779198
785	Phosphorylation	CRTLLHCSGLPNHLW HHHHHHCCCCCCCEE	32.39	19779198
800	Phosphorylation	FSAVEFSTIIRNSLV EEEHHHHHHHHHCCC	26.24	19779198
846	Ubiquitination	NNHNPDSKIHPRGIP CCCCCCCCCCCCCCC	53.03	17644757
874	Ubiquitination	IIYLPSLKKTVDTTN EEEECCCCEEECCCC	51.22	17644757
875	Ubiquitination	IYLPSLKKTVDTTNY EEECCCCEEECCCCE	60.10	17644757
891	Ubiquitination	ILQNNQTKLDQFDYD EEECCCCCCCCCCCC	40.06	17644757
968	Ubiquitination	LDKEPVQKVRAPKEV CCCCHHHCCCCCCCC	33.64	15699485
973	Ubiquitination	VQKVRAPKEVDADIS HHCCCCCCCCCCCHH	70.19	17644757
991	Phosphorylation	ILPSTIRSRTPHIIN CCCHHHHCCCCCEEC	36.33	30377154
993	Phosphorylation	PSTIRSRTPHIINKE CHHHHCCCCCEECCC	22.06	21440633
999	Ubiquitination	RTPHIINKESTEMGG CCCCEECCCCCCCCC	42.50	17644757
1010	Phosphorylation	EMGGTIESDTTSPRH CCCCEEECCCCCCCC	36.08	21551504
1012	Phosphorylation	GGTIESDTTSPRHSS CCEEECCCCCCCCCC	38.15	22369663
1013	Phosphorylation	GTIESDTTSPRHSST CEEECCCCCCCCCCC	41.55	21440633
1014	Phosphorylation	TIESDTTSPRHSSTF EEECCCCCCCCCCCE	23.25	22369663
1018	Phosphorylation	DTTSPRHSSTFTARN CCCCCCCCCCEEECC	32.14	24961812
1019	Phosphorylation	TTSPRHSSTFTARNQ CCCCCCCCCEEECCC	22.78	24961812
1020	Phosphorylation	TSPRHSSTFTARNQK CCCCCCCCEEECCCC	28.20	24961812
1027	Ubiquitination	TFTARNQKRPGSPND CEEECCCCCCCCCCC	65.20	17644757
1031	Phosphorylation	RNQKRPGSPNDMIDL CCCCCCCCCCCCCCC	24.18	17330950
1052	Ubiquitination	NYGLENIKTTRLGGT HHCCCCCEEEECCCC	56.26	17644757
1053	Phosphorylation	YGLENIKTTRLGGTE HCCCCCEEEECCCCC	17.22	24961812
1054	Phosphorylation	GLENIKTTRLGGTEE CCCCCEEEECCCCCC	20.92	24961812
1059	Phosphorylation	KTTRLGGTEEPYIQR EEEECCCCCCCCCCC	35.06	24961812
1063	Phosphorylation	LGGTEEPYIQRNSDT CCCCCCCCCCCCCCC	16.99	21440633
1068	Phosphorylation	EPYIQRNSDTNIKYR CCCCCCCCCCCCEEE	48.26	25752575
1070	Phosphorylation	YIQRNSDTNIKYRTT CCCCCCCCCCEEECC	38.37	27017623
1073	Ubiquitination	RNSDTNIKYRTTNST CCCCCCCEEECCCCC	30.65	17644757
1076	Phosphorylation	DTNIKYRTTNSTPSI CCCCEEECCCCCCCC	27.52	24961812
1077	Phosphorylation	TNIKYRTTNSTPSID CCCEEECCCCCCCCC	20.41	24961812
1079	Phosphorylation	IKYRTTNSTPSIDDR CEEECCCCCCCCCCC	39.33	24961812
1080	Phosphorylation	KYRTTNSTPSIDDRS EEECCCCCCCCCCCC	24.11	24961812
1082	Phosphorylation	RTTNSTPSIDDRSSN ECCCCCCCCCCCCCC	38.44	25704821
1087	Phosphorylation	TPSIDDRSSNSESTT CCCCCCCCCCCCCCC	40.65	17330950
1088	Phosphorylation	PSIDDRSSNSESTTP CCCCCCCCCCCCCCC	45.31	21440633
1090	Phosphorylation	IDDRSSNSESTTPII CCCCCCCCCCCCCEE	34.57	17330950
1092	Phosphorylation	DRSSNSESTTPIISI CCCCCCCCCCCEEEE	37.08	21440633
1093	Phosphorylation	RSSNSESTTPIISIE CCCCCCCCCCEEEEE	32.32	17330950
1094	Phosphorylation	SSNSESTTPIISIET CCCCCCCCCEEEEEE	23.05	17330950
1098	Phosphorylation	ESTTPIISIETKAVC CCCCCEEEEEEEEEC	18.32	24961812
1101	Phosphorylation	TPIISIETKAVCDNT CCEEEEEEEEECCCC	23.72	24961812
1102	Ubiquitination	PIISIETKAVCDNTP CEEEEEEEEECCCCC	26.49	17644757
1108	Phosphorylation	TKAVCDNTPSIDTDP EEEECCCCCCCCCCC	12.74	21551504
1110	Phosphorylation	AVCDNTPSIDTDPPE EECCCCCCCCCCCCC	30.93	28889911
1113	Phosphorylation	DNTPSIDTDPPEYRS CCCCCCCCCCCCCCC	49.05	27017623
1125	Phosphorylation	YRSSDHATPNIMPDK CCCCCCCCCCCCCCC	17.28	17330950
1132	Ubiquitination	TPNIMPDKSSKNVTA CCCCCCCCCCCCCCC	51.24	17644757
1141	Phosphorylation	SKNVTADSILDDLPL CCCCCCCHHHCCCCC	23.68	21440633
1155	Phosphorylation	LPDLTHKSPTDTSDV CCCCCCCCCCCHHHH	25.98	28889911
1174	Phosphorylation	PHIHSRQTNSSLGGM CCCCCCCCCCCCCCC	35.64	27017623
1176	Phosphorylation	IHSRQTNSSLGGMDD CCCCCCCCCCCCCCC	30.26	27017623
1177	Phosphorylation	HSRQTNSSLGGMDDS CCCCCCCCCCCCCCC	32.86	19779198
1184	Phosphorylation	SLGGMDDSNVLTTTK CCCCCCCCCCEECCC	25.27	27017623
1188	Phosphorylation	MDDSNVLTTTKSKKR CCCCCCEECCCCCCC	28.30	27017623
1189	Phosphorylation	DDSNVLTTTKSKKRS CCCCCEECCCCCCCC	28.24	27017623
1190	Phosphorylation	DSNVLTTTKSKKRSL CCCCEECCCCCCCCC	28.25	27017623
1191	Ubiquitination	SNVLTTTKSKKRSLE CCCEECCCCCCCCCC	59.18	23749301
1192	Phosphorylation	NVLTTTKSKKRSLED CCEECCCCCCCCCCC	41.12	19779198
1193	Ubiquitination	VLTTTKSKKRSLEDN CEECCCCCCCCCCCC	54.48	15699485
1194	Ubiquitination	LTTTKSKKRSLEDNE EECCCCCCCCCCCCC	55.07	15699485
1214	Ubiquitination	SRDTWNNKNMRSLEP EHHHCCCCCCCCCCC	49.24	17644757
1257	Ubiquitination	DEAITYNKDNKEKDR CEEEEECCCCHHHHH	52.87	17644757
1271	Ubiquitination	RYVEAYHKEISQLLK HHHHHHHHHHHHHHH	44.03	15699485
1278	Ubiquitination	KEISQLLKMNTWDTN HHHHHHHHHCCCCCC	38.40	15699485
1297	Ubiquitination	RNDIDPKKVINSMFI CCCCCHHHHHCEEEE	54.45	17644757
1301	Phosphorylation	DPKKVINSMFIFNKK CHHHHHCEEEEEECC	12.16	24909858
1307	Ubiquitination	NSMFIFNKKRDGTHK CEEEEEECCCCCCCC	38.14	17644757
1308	Ubiquitination	SMFIFNKKRDGTHKA EEEEEECCCCCCCCE	57.75	17644757
1400	Ubiquitination	RKSLYGLKQSGANWY HHHHHCCHHCCCCHH	37.75	15699485
1402	Phosphorylation	SLYGLKQSGANWYET HHHCCHHCCCCHHHH	37.98	19779198
1407	Phosphorylation	KQSGANWYETIKSYL HHCCCCHHHHHHHHH	11.73	19779198
1411	Ubiquitination	ANWYETIKSYLINCC CCHHHHHHHHHHHCC	40.23	17644757
1455	Ubiquitination	SKDLNANKKIITTLK HCCCCCCHHHHHHHH	42.83	17644757
1456	Ubiquitination	KDLNANKKIITTLKK CCCCCCHHHHHHHHH	38.87	17644757
1462	Ubiquitination	KKIITTLKKQYDTKI HHHHHHHHHHCCCEE	35.42	17644757
1463	Ubiquitination	KIITTLKKQYDTKII HHHHHHHHHCCCEEE	58.14	17644757
1468	Ubiquitination	LKKQYDTKIINLGEG HHHHCCCEEEECCCC	38.40	17644757
1489	Ubiquitination	DILGLEIKYQRSKYM EECCEEEEECHHHHH	26.42	17644757
1510	Ubiquitination	SLTEKLPKLNVPLNP HHHHCCCCCCCCCCC	64.23	17644757
1518	Ubiquitination	LNVPLNPKGKKLRAP CCCCCCCCCCCCCCC	80.45	17644757
1553	Ubiquitination	EKVHEMQKLIGLASY HHHHHHHHHHHHHHH	40.54	17644757
1564	Ubiquitination	LASYVGYKFRFDLLY HHHHCCHHHHHHHHH	24.92	22106047
1619	Ubiquitination	KPTKPDNKLVAISDA CCCCCCCCEEEEEEC	52.28	17644757
1635	Ubiquitination	YGNQPYYKSQIGNIF CCCCCCEECCCCCEE	30.00	17644757
1647	Ubiquitination	NIFLLNGKVIGGKST CEEEECCEEECCCCC	29.61	17644757
1652	Ubiquitination	NGKVIGGKSTKASLT CCEEECCCCCCEEEE	50.14	17644757
1655	Ubiquitination	VIGGKSTKASLTCTS EECCCCCCEEEEECC	42.97	17644757
1690	Ubiquitination	HLVQELNKKPIIKGL HHHHHHCCCCCHHHH	72.97	17644757
1691	Ubiquitination	LVQELNKKPIIKGLL HHHHHCCCCCHHHHH	40.14	17644757
1704	Phosphorylation	LLTDSRSTISIIKST HHCCCCHHHEEEECC	20.03	21440633
1711	Phosphorylation	TISIIKSTNEEKFRN HHEEEECCCHHHHHH	41.46	27017623
1724	Ubiquitination	RNRFFGTKAMRLRDE HHHHCCCCEEEECCC	40.33	23749301
1745	Ubiquitination	YVYYIETKKNIADVM EEEEEEECCCHHHHH	30.91	17644757
1746	Ubiquitination	VYYIETKKNIADVMT EEEEEECCCHHHHHC	62.09	23749301
1753	Phosphorylation	KNIADVMTKPLPIKT CCHHHHHCCCCCCCC	29.38	20377248
1754	Ubiquitination	NIADVMTKPLPIKTF CHHHHHCCCCCCCCC	26.85	23749301
1759	Ubiquitination	MTKPLPIKTFKLLTN HCCCCCCCCCHHHHC	46.07	22817900
1762	Ubiquitination	PLPIKTFKLLTNKWI CCCCCCCHHHHCCCC	48.06	15699485

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YD22B_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YD22B_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YD22B_YEAST !!

Protein-Protein Interaction

Oops, there are no PPI records of YD22B_YEAST !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.