dbPTM

YCS1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YCS1_SCHPO
UniProt AC	O74901
Protein Name	Uncharacterized protein CC613.01
Gene Name	SPCC613.01, SPCC757.14
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	497
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MSTTTETVTWSQYKPQETQRRLSRSSTITPSVSEYRSGFSKTAFGNIELEEIPDKQGNITRATSNLESNSYPKALDPDACPPKRSIALVLLNNLMSEMSLTIALPISAAYTEILGGTDAFSGLVIGIPTMISLVCLYPMLRFANPKSANGYTLYFRPLIVSCISQIIGHLLYSLAYRAQWLYLILIGRMCSGVGFTMFLYHKTYLTDKNFVGQNRSTFLATLNILAQILGSMAGAFLGGILAKASMHLTDPIWNQYTAGSWFMLFIWIVYSIFLSIFFKEVRVGNTATNVRKPESFTGKTAPLSFKQKFMLCFLSMAAFISIFNVAGYQTSVPIYAKALYHYNPFQSGNFLSLSSLVIAPFVFFSTFLSKWLEDRQIMLYGFMMGIVALIVHLVLDAVHKIPVQPYFVLYSIMQFGFSVGSAPLVSLATKQLHPKYHMITGVVVQVGISIGETVGSICGGAIFDITTVGFIAMNLGIALLVFIQLLYLWTFIKTKTG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	QETQRRLSRSSTITP HHHHHHHHCCCCCCC	28.45	29996109
25	Phosphorylation	TQRRLSRSSTITPSV HHHHHHCCCCCCCCH	28.58	29996109
26	Phosphorylation	QRRLSRSSTITPSVS HHHHHCCCCCCCCHH	23.79	29996109
27	Phosphorylation	RRLSRSSTITPSVSE HHHHCCCCCCCCHHH	30.07	29996109
29	Phosphorylation	LSRSSTITPSVSEYR HHCCCCCCCCHHHHH	15.03	29996109
31	Phosphorylation	RSSTITPSVSEYRSG CCCCCCCCHHHHHCC	29.62	25720772
33	Phosphorylation	STITPSVSEYRSGFS CCCCCCHHHHHCCCC	32.99	25720772
60	Phosphorylation	PDKQGNITRATSNLE CCCCCCCEECCCCCC	20.46	21712547
63	Phosphorylation	QGNITRATSNLESNS CCCCEECCCCCCCCC	18.17	25720772
64	Phosphorylation	GNITRATSNLESNSY CCCEECCCCCCCCCC	38.13	28889911
68	Phosphorylation	RATSNLESNSYPKAL ECCCCCCCCCCCCCC	33.95	21712547
70	Phosphorylation	TSNLESNSYPKALDP CCCCCCCCCCCCCCC	52.68	21712547
71	Phosphorylation	SNLESNSYPKALDPD CCCCCCCCCCCCCCC	17.01	21712547
295	Phosphorylation	TNVRKPESFTGKTAP CCCCCCCCCCCCCCC	36.31	28889911
297	Phosphorylation	VRKPESFTGKTAPLS CCCCCCCCCCCCCCC	47.23	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YCS1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YCS1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YCS1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YCS1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YCS1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-64 AND SER-295, AND MASSSPECTROMETRY.	18257517 [Abstract]