dbPTM

YCKC_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YCKC_SCHPO
UniProt AC	Q9Y7N9
Protein Name	PX domain-containing protein C1450.12
Gene Name	SPCC1450.12
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	821
Subcellular Localization	Mitochondrion membrane Peripheral membrane protein.
Protein Description
Protein Sequence	MDTASPEEIDALKRHYLKKELFSLLIADELNFVSEPTNLDHLGSPFVEKGKSVIPYEKSQIPVLRFIFKRFILTFPFLDPDSQNQLWNVNFRNLLKSLSKSNVSVLPDDSDATHLHKWLLKFQNMLTLLMSRAFHSIQDEKNINIELLDTPKLEKDLHKSELQQKPNILEAYVLGVRQSTQAKMLRTKRVYEYLIKVSYEENTFFIARKYSDFSHFHHLLLKSYPNAYVPRLPPKDDHDTYLNSSEDSTLSPLPSRSSDTNDPQSDSQHVLRQERMRIELRQYIKNILNDDELHLTEEVLSFLTDDPVTLTASELTDINFRQELDVIRQLEQQKFVEIASQRAKELDVYMEEFKRSLTENNGFTTLFTELKEKNSISELSPSLQKTIEWARVNLASTIYDTFIGKEKSLETYLQIKKMHQLFPYTVIKNIMRFSNPLSVMKRILDTLLAQPFGMKSLFQRLLSISLNENVRAIHKLISRYEARIVSPEILTKIQEQVENPCKAAREVLEKKQMKRHDYLYFILISDDVPPKLPDNLIRRVYAERTAWKAALDSEDYPTDPTVIRRSKRYGYMMKLMHLYAKQFNKRRSISLISEGATGEIMKSMVDSPELNPNILVEQFIDLVRRHEDSFYDFVHRVYLHDSGLFASLMEWIENIIGFLRQGTSAPIDMDLVVDALDEESRQALDVELNKLLKWNQRKKSALFLRKTTKYIPGEETSLPVTMDELGIDEEIMAELRGDEDDQDENDQVTKVEEEHMEDDDSVEEFDPIIEERQRMKRKANRPANIIPPKPKLRTVKTLLPAFKEQVYPILHKFVSENEKDI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
59	Phosphorylation	SVIPYEKSQIPVLRF CCCCCCHHHCCHHHH	22.77	25720772
150	Phosphorylation	INIELLDTPKLEKDL CCEEECCCHHHHHHH	23.46	24763107
160	Phosphorylation	LEKDLHKSELQQKPN HHHHHCHHHHHHCCC	32.56	21712547
245	Phosphorylation	HDTYLNSSEDSTLSP CCCCCCCCCCCCCCC	44.33	27738172
251	Phosphorylation	SSEDSTLSPLPSRSS CCCCCCCCCCCCCCC	25.20	29996109
255	Phosphorylation	STLSPLPSRSSDTND CCCCCCCCCCCCCCC	53.10	29996109
257	Phosphorylation	LSPLPSRSSDTNDPQ CCCCCCCCCCCCCCC	36.58	29996109
258	Phosphorylation	SPLPSRSSDTNDPQS CCCCCCCCCCCCCCC	47.55	29996109
260	Phosphorylation	LPSRSSDTNDPQSDS CCCCCCCCCCCCCCH	43.39	28889911
265	Phosphorylation	SDTNDPQSDSQHVLR CCCCCCCCCHHHHHH	44.62	19547744
597	Phosphorylation	SLISEGATGEIMKSM EEECCCCCHHHHHHH	46.32	28889911
761	Phosphorylation	EHMEDDDSVEEFDPI HHCCCCCCHHHHHHH	38.12	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YCKC_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YCKC_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YCKC_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YCKC_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YCKC_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-260; THR-597 ANDSER-761, AND MASS SPECTROMETRY.	18257517 [Abstract]