dbPTM

YC58_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YC58_SCHPO
UniProt AC	O94708
Protein Name	Uncharacterized protein C1259.08
Gene Name	SPCC1259.08
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	394
Subcellular Localization	Nucleus .
Protein Description
Protein Sequence	MTGLLSILLHYKGNGDLATTDIPSHEKIPSAKRTAVQFCIGPTHEQSPRMSTVSQGRVTFAVLPTKPKDEVTSMKANGSRQSSCIVSNARKRQSVHCLSRSPIPSTRLKENDSRLCSPLASPTGGLKRPAKVSFALANTPSRKGNLVPQSPRRTIATTCKGVLEDVLKKDNELKFNDSDEEDEVDDEEIESFNSFSRKMQTISNSRYRGSPKPNIEKQSCSSESDRVSQISDDEEDEEGSADEEDEEDSDVELSESSLSDDEDSPLRCPSTPVQTAAAPNESQIPDDTDFVPGTFDEDQPACLAFACSLTHANSKRSIMLPQDIDPTFPDSEPEDDGHASSTVGSLSKEEARFKAKAKWNYKSSFSAHVSSEVLRNSKSPPLDIARKAVGAHRV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
117	Phosphorylation	ENDSRLCSPLASPTG CCCCCCCCCCCCCCC	27.78	28889911
121	Phosphorylation	RLCSPLASPTGGLKR CCCCCCCCCCCCCCC	30.58	28889911
123	Phosphorylation	CSPLASPTGGLKRPA CCCCCCCCCCCCCCC	41.19	29996109
133	Phosphorylation	LKRPAKVSFALANTP CCCCCEEEEEECCCC	12.23	29996109
139	Phosphorylation	VSFALANTPSRKGNL EEEEECCCCCCCCCC	19.62	29996109
150	Phosphorylation	KGNLVPQSPRRTIAT CCCCCCCCCCCHHHH	17.82	29996109
178	Phosphorylation	NELKFNDSDEEDEVD CCCCCCCCCCCCCCC	48.29	28889911
207	Phosphorylation	QTISNSRYRGSPKPN HHHCCCCCCCCCCCC	21.10	25720772
210	Phosphorylation	SNSRYRGSPKPNIEK CCCCCCCCCCCCCCC	22.28	29996109
377	Phosphorylation	SSEVLRNSKSPPLDI CHHHHHCCCCCCHHH	28.24	29996109
379	Phosphorylation	EVLRNSKSPPLDIAR HHHHCCCCCCHHHHH	31.41	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YC58_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YC58_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YC58_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YC58_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YC58_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-117; SER-121 ANDSER-379, AND MASS SPECTROMETRY.	18257517 [Abstract]