YBWC_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YBWC_SCHPO
• UniProt AC: O94670
• Protein Name: Uncharacterized protein C651.12c
• Gene Name: SPBC651.12c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 273
• Subcellular Localization: Nucleus . Cytoplasm, cytoskeleton, spindle .
• Protein Sequence: MSSKKVKYNPRKSASQNEATSASAGSKAFGFNSAKKEKLHRMALSMEAIEDVEDQSFNGKSSNLVRKRRGLDEDIDEFSSSSEDERKPARHPQSSSQKPFASSTYNVELPTSPTKITNIGQSSPRALRYLSPESQRIKNAKMKSPISTHLAKYSIHHMGTPPSKPSFLSSSVSSPASSKQKSLFQCTKDLEKRYINRVHRSSETELVQLSSIKVLDRFLSDIYLVEAEKNEEKCTVLLLKRSNTDVDNSSSLSLTLPLCKFTKNGHQVHIHPC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
102	Phosphorylation	SSQKPFASSTYNVEL CCCCCCCCCEEEEEC	24.48	21712547
111	Phosphorylation	TYNVELPTSPTKITN EEEEECCCCCCCCEE	61.02	21712547
112	Phosphorylation	YNVELPTSPTKITNI EEEECCCCCCCCEEC	28.74	21712547
122	Phosphorylation	KITNIGQSSPRALRY CCEECCCCCHHHHHH	36.78	21712547
123	Phosphorylation	ITNIGQSSPRALRYL CEECCCCCHHHHHHC	15.54	28889911
129	Phosphorylation	SSPRALRYLSPESQR CCHHHHHHCCHHHHH	16.63	29996109
131	Phosphorylation	PRALRYLSPESQRIK HHHHHHCCHHHHHHH	20.07	28889911
134	Phosphorylation	LRYLSPESQRIKNAK HHHCCHHHHHHHHCC	28.30	21712547
144	Phosphorylation	IKNAKMKSPISTHLA HHHCCCCCCHHHHHH	24.78	24763107
147	Phosphorylation	AKMKSPISTHLAKYS CCCCCCHHHHHHHHH	17.10	25720772
148	Phosphorylation	KMKSPISTHLAKYSI CCCCCHHHHHHHHHH	22.94	21712547
170	Phosphorylation	SKPSFLSSSVSSPAS CCCCCCCCCCCCCCC	36.59	24763107
174	Phosphorylation	FLSSSVSSPASSKQK CCCCCCCCCCCHHHH	23.48	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YBWC_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YBWC_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YBWC_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
REB1_SCHPO	reb1	genetic	22681890
RAD55_SCHPO	rad55	genetic	22681890
SWD1_SCHPO	swd1	genetic	22681890
TOM70_SCHPO	tom70	genetic	22681890
NPY1_SCHPO	SPBC1778.03c	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-123, AND MASSSPECTROMETRY.
PubMed: 18257517