YBS7_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YBS7_SCHPO
• UniProt AC: O94497
• Protein Name: Uncharacterized serine-rich protein C18E5.07
• Gene Name: SPBC18E5.07
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 615
• Protein Sequence: MSETSSNSPASGSKEAVPKSLAGSTSNIPNELFVGPDGRPLSQNAQGASKSSSKVVPQALVPEDDIRAVEGILNYGGSNDNRPVSHTHTFVELQKSHQNHLTENDRNFGTSRLDDVAPNADGVRRLRTSGSSTGLSNAPPSANVSKASSNLSLASLAKTQPERATPEVCVPLNPDTGSVPLIHPEQTDRGLPYAPDEKFHNSGSLKLPKGASLEDLSRSPSRAVLNEDGNVDECAPPEPWENEYNEVLDDVENAVVGTSPLEYTSKPLAANRQRSTADLTESDNICGLTAGKSDPVTDVDESQTIDEQSIPEAEKGFYTKDGEGTAGLPFDIVSNLDIPNENAHESSRSKKKHTGPSLSSASQPSAASSSSSSEPSNLDKINDVKKNIEVSANEPQPRPVKEDVPKSQVGGETDTTDVINNSTPKEETEESPSTELPETGKEQPPNKAEPAVPTEASSTKPSEAAEESTPRFSVRPNKFTGSRAGFVAALESRLQKGPLMRSFVPNKSKSPSGTKSPASGETSEAGVKETETTTSSESALPDARKSRARGPVRRPPTSVNTKPSFSVSGIDVFLNLPQSSVMKKKGVETRKEVEPKEEAVIPEEDVEVEVETEEQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	SKEAVPKSLAGSTSN CCCCCCHHHCCCCCC	19.85	24763107
24	Phosphorylation	VPKSLAGSTSNIPNE CCHHHCCCCCCCCCC	24.05	27738172
25	Phosphorylation	PKSLAGSTSNIPNEL CHHHCCCCCCCCCCE	25.52	21712547
42	Phosphorylation	GPDGRPLSQNAQGAS CCCCCCCCCCCCCCC	24.87	21712547
49	Phosphorylation	SQNAQGASKSSSKVV CCCCCCCCCCCCCCC	39.64	29996109
128	Phosphorylation	DGVRRLRTSGSSTGL CCCEEECCCCCCCCC	41.87	29996109
129	Phosphorylation	GVRRLRTSGSSTGLS CCEEECCCCCCCCCC	30.18	28889911
131	Phosphorylation	RRLRTSGSSTGLSNA EEECCCCCCCCCCCC	25.21	25720772
132	Phosphorylation	RLRTSGSSTGLSNAP EECCCCCCCCCCCCC	29.98	29996109
133	Phosphorylation	LRTSGSSTGLSNAPP ECCCCCCCCCCCCCC	43.79	29996109
136	Phosphorylation	SGSSTGLSNAPPSAN CCCCCCCCCCCCCCC	32.08	25720772
148	Phosphorylation	SANVSKASSNLSLAS CCCHHHHHCCCCHHH	24.40	25720772
149	Phosphorylation	ANVSKASSNLSLASL CCHHHHHCCCCHHHH	46.80	28889911
152	Phosphorylation	SKASSNLSLASLAKT HHHHCCCCHHHHHCC	26.58	28889911
155	Phosphorylation	SSNLSLASLAKTQPE HCCCCHHHHHCCCCC	33.87	24763107
159	Phosphorylation	SLASLAKTQPERATP CHHHHHCCCCCCCCC	43.69	29996109
165	Phosphorylation	KTQPERATPEVCVPL CCCCCCCCCCEEEEC	26.63	29996109
176	Phosphorylation	CVPLNPDTGSVPLIH EEECCCCCCCCCCCC	32.39	27738172
202	Phosphorylation	PDEKFHNSGSLKLPK CCCCCCCCCCCCCCC	22.61	25720772
204	Phosphorylation	EKFHNSGSLKLPKGA CCCCCCCCCCCCCCC	23.35	21712547
212	Phosphorylation	LKLPKGASLEDLSRS CCCCCCCCHHHHCCC	40.74	28889911
217	Phosphorylation	GASLEDLSRSPSRAV CCCHHHHCCCCCCEE	42.93	29996109
219	Phosphorylation	SLEDLSRSPSRAVLN CHHHHCCCCCCEEEC	24.69	28889911
221	Phosphorylation	EDLSRSPSRAVLNED HHHCCCCCCEEECCC	33.83	29996109
275	Phosphorylation	LAANRQRSTADLTES CHHCCCCCCCCCCCC	21.43	28889911
276	Phosphorylation	AANRQRSTADLTESD HHCCCCCCCCCCCCC	26.78	28889911
280	Phosphorylation	QRSTADLTESDNICG CCCCCCCCCCCCCCC	33.71	25720772
293	Phosphorylation	CGLTAGKSDPVTDVD CCCCCCCCCCCCCCC	46.35	25720772
297	Phosphorylation	AGKSDPVTDVDESQT CCCCCCCCCCCHHHC	35.38	28889911
302	Phosphorylation	PVTDVDESQTIDEQS CCCCCCHHHCCCHHH	28.32	29996109
304	Phosphorylation	TDVDESQTIDEQSIP CCCCHHHCCCHHHCC	39.41	29996109
309	Phosphorylation	SQTIDEQSIPEAEKG HHCCCHHHCCHHHCC	37.75	25720772
325	Phosphorylation	YTKDGEGTAGLPFDI ECCCCCCCCCCCCEE	17.16	29996109
334	Phosphorylation	GLPFDIVSNLDIPNE CCCCEEEECCCCCCC	31.82	24763107
346	Phosphorylation	PNENAHESSRSKKKH CCCCCCHHHHCCCCC	22.60	21712547
354	Phosphorylation	SRSKKKHTGPSLSSA HHCCCCCCCCCCCCC	60.72	27738172
359	Phosphorylation	KHTGPSLSSASQPSA CCCCCCCCCCCCCCC	28.35	27738172
365	Phosphorylation	LSSASQPSAASSSSS CCCCCCCCCCCCCCC	28.91	27738172
368	Phosphorylation	ASQPSAASSSSSSEP CCCCCCCCCCCCCCC	30.39	21712547
369	Phosphorylation	SQPSAASSSSSSEPS CCCCCCCCCCCCCCC	29.52	21712547
371	Phosphorylation	PSAASSSSSSEPSNL CCCCCCCCCCCCCCH	39.57	21712547
372	Phosphorylation	SAASSSSSSEPSNLD CCCCCCCCCCCCCHH	40.44	21712547
373	Phosphorylation	AASSSSSSEPSNLDK CCCCCCCCCCCCHHH	56.31	24763107
407	Phosphorylation	VKEDVPKSQVGGETD CCCCCCHHHCCCCCC	24.83	21712547
422	Phosphorylation	TTDVINNSTPKEETE CCCCCCCCCCHHHCC	41.41	29996109
423	Phosphorylation	TDVINNSTPKEETEE CCCCCCCCCHHHCCC	40.27	21712547
428	Phosphorylation	NSTPKEETEESPSTE CCCCHHHCCCCCCCC	46.26	29996109
431	Phosphorylation	PKEETEESPSTELPE CHHHCCCCCCCCCCC	20.23	24763107
492	Phosphorylation	GFVAALESRLQKGPL HHHHHHHHHHHHCCC	38.86	25720772
508	Phosphorylation	RSFVPNKSKSPSGTK HHCCCCCCCCCCCCC	45.03	21712547
510	Phosphorylation	FVPNKSKSPSGTKSP CCCCCCCCCCCCCCC	31.24	25720772
512	Phosphorylation	PNKSKSPSGTKSPAS CCCCCCCCCCCCCCC	67.21	25720772
514	Phosphorylation	KSKSPSGTKSPASGE CCCCCCCCCCCCCCC	32.46	28889911
516	Phosphorylation	KSPSGTKSPASGETS CCCCCCCCCCCCCCC	26.07	28889911
519	Phosphorylation	SGTKSPASGETSEAG CCCCCCCCCCCCCCC	40.31	24763107
522	Phosphorylation	KSPASGETSEAGVKE CCCCCCCCCCCCCEE	35.08	29996109
523	Phosphorylation	SPASGETSEAGVKET CCCCCCCCCCCCEEC	22.58	21712547
530	Phosphorylation	SEAGVKETETTTSSE CCCCCEECEECCCCH	32.68	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YBS7_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YBS7_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YBS7_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YBS7_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-149; SER-152; SER-219;SER-275; THR-276; THR-297; THR-514 AND SER-516, AND MASS SPECTROMETRY.
PubMed: 18257517