YBOX3_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YBOX3_RAT
• UniProt AC: Q62764
• Protein Name: Y-box-binding protein 3
• Gene Name: Ybx3
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 361
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity)..
• Protein Sequence: MSEAGEATTGGTTLPQAAADAPAAAPPDPAPKSPAASGAPQAPAPAALLAGSPGGDAAPGPAPASSAPAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYRQRRFPPYHVGQTFDRRSRVFPHPNRMQAGEIGEMKDGVPEGAQLQVHRNPTYRPRFRRGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRPRPLNAVSQDGKETKAGEAPTENPAPATEQSSAE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSEAGEATT ------CCCCCCCCC		27097102
2	Acetylation	------MSEAGEATT ------CCCCCCCCC		-
8	Phosphorylation	MSEAGEATTGGTTLP CCCCCCCCCCCCCCC		27097102
9	Phosphorylation	SEAGEATTGGTTLPQ CCCCCCCCCCCCCCH		27097102
12	Phosphorylation	GEATTGGTTLPQAAA CCCCCCCCCCCHHHH		27097102
13	Phosphorylation	EATTGGTTLPQAAAD CCCCCCCCCCHHHHC		27097102
33	Phosphorylation	PPDPAPKSPAASGAP CCCCCCCCCCCCCCC		29779826
37	Phosphorylation	APKSPAASGAPQAPA CCCCCCCCCCCCCCC		27097102
52	Phosphorylation	PAALLAGSPGGDAAP CHHHHCCCCCCCCCC		27097102
65	Phosphorylation	APGPAPASSAPAGSE CCCCCCCCCCCCCCH		27097102
66	Phosphorylation	PGPAPASSAPAGSED CCCCCCCCCCCCCHH		27097102
71	Phosphorylation	ASSAPAGSEDAEKKV CCCCCCCCHHHHHHH		27097102
105	Acetylation	FINRNDTKEDVFVHQ EECCCCCCCCEEEEH		22644193
116	Acetylation	FVHQTAIKKNNPRKY EEEHHHHHCCCHHHH		1894127
123	Phosphorylation	KKNNPRKYLRSVGDG HCCCHHHHHEECCCC		23984901
126	Phosphorylation	NPRKYLRSVGDGETV CHHHHHEECCCCCEE		22108457
132	Phosphorylation	RSVGDGETVEFDVVE EECCCCCEEEEEEEC		23984901
184	Phosphorylation	RRGPPRNYAGEEEEE CCCCCCCCCCCCCCC		28689409
193	Phosphorylation	GEEEEEGSGSSEGFE CCCCCCCCCCCCCCC		22673903
195	Phosphorylation	EEEEGSGSSEGFEPP CCCCCCCCCCCCCCC		22673903
196	Phosphorylation	EEEGSGSSEGFEPPA CCCCCCCCCCCCCCC		22673903
243	Methylation	QTFDRRSRVFPHPNR CCCCCCCCCCCCCCC		-
313	Phosphorylation	ANGPNQPSARRGFRR HCCCCCHHHHHHCCC		23984901
315	Methylation	GPNQPSARRGFRRPY CCCCHHHHHHCCCCC		-
335	Phosphorylation	PRPLNAVSQDGKETK CCCCCCCCCCCCCCC		27097102
348	Phosphorylation	TKAGEAPTENPAPAT CCCCCCCCCCCCCCC		28432305
355	Phosphorylation	TENPAPATEQSSAE- CCCCCCCCCCCCCC-		27097102
358	Phosphorylation	PAPATEQSSAE---- CCCCCCCCCCC----		27097102
359	Phosphorylation	APATEQSSAE----- CCCCCCCCCC-----		27097102

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YBOX3_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YBOX3_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YBOX3_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of YBOX3_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.