dbPTM

YBH6_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YBH6_SCHPO
UniProt AC	O59714
Protein Name	Uncharacterized membrane protein C3B8.06
Gene Name	SPBC3B8.06
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	511
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MDGMHMNSTGDNPIEIDFENYANHMNKFLMAHIICMIIAYVFILPAGIVLAMAKSKAHIPVQIVYVILTLIGYIFAHISHHKASPENYYKGNIHRPVGRFFMWITFLIAIVGITTSILKKRMLKEYQPAAEAPGAMEDPEQALQRNSLDDGAPLLPREGNSSDEYLPPQSSRRDVSSEKPSIPSISFINIRSWRTIPKKWCVLQVLRYFHRILGHLWLYVGFFESCTGIVLLAGIFKGQHIFNGLAHWIKGAIFLWYGILSFGEYLGAFSEYGWAWNVVPKQLSEKRFAKYVPTKEMVESFLLFAYGVSNVWLEHLGNTDGKWNHHDLQHASLAFMLWWAGLCGILVESKVVHRLLNATLSATLGQRRSEDSEHSENGLPSYNVFPALTVFFTGIMMSAHDQTNHVSTVIHVLWGRLLAAAAIARICTYIMLYLKPPSSPWPTRPPTEIITSFCLICGGAMFMASSYDVVNKIRLNEMSPMLIMNISVAFTCIVMGLEVMFLILKGYASSR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
147	Phosphorylation	EQALQRNSLDDGAPL HHHHHHCCCCCCCCC	35.05	28889911
161	Phosphorylation	LLPREGNSSDEYLPP CCCCCCCCCCCCCCC	50.45	28889911
162	Phosphorylation	LPREGNSSDEYLPPQ CCCCCCCCCCCCCCC	38.16	28889911
165	Phosphorylation	EGNSSDEYLPPQSSR CCCCCCCCCCCCCCC	29.51	25720772
176	Phosphorylation	QSSRRDVSSEKPSIP CCCCCCCCCCCCCCC	36.75	25720772
177	Phosphorylation	SSRRDVSSEKPSIPS CCCCCCCCCCCCCCC	49.87	25720772
181	Phosphorylation	DVSSEKPSIPSISFI CCCCCCCCCCCEEEE	59.19	25720772
184	Phosphorylation	SEKPSIPSISFINIR CCCCCCCCEEEEEEC	29.24	25720772
186	Phosphorylation	KPSIPSISFINIRSW CCCCCCEEEEEECCC	25.14	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YBH6_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YBH6_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YBH6_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YBH6_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YBH6_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-147; SER-161 ANDSER-162, AND MASS SPECTROMETRY.	18257517 [Abstract]