dbPTM

YAEC_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YAEC_SCHPO
UniProt AC	Q09852
Protein Name	Putative inorganic phosphate transporter C23D3.12
Gene Name	SPAC23D3.12
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	559
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	High-affinity transporter for external inorganic phosphate..
Protein Sequence	MNRLNPFSKSHSKNSNENNEVSLADVAESDTRRHWLGLTKREFKLMGFAGAGFFLDSYDLFIINLVSPIYEYLYWGGLEGKKPHYPSGIHGLVNAAANIGNVFGQILFGFMGDFFGRKFVYGKEMIVVIIATVLVIALPKSIPTPLGKMMWIFAWRWLLGLGIGGDYPMSATITSERSLLSRRGTLLSIVFSFQGFGTLAGAIVTIILLACFEKPLNQRGEYTKLEGVWRLQMGLALVPALLVLIPRLTMKESKSYEQSKALNKYTDNDTYIADDDEPKKDNQNVVEEKQINLTTSSDSHPTSTEDFGDKRASTVPTSENTSGFIEYFSQWHHFKHLLATAVSWFLLDIAFYGVNLNQSVILKAIGFSSGKNEYHTLMRGAIGNLIIAIAGYVPGYWFTVFLVEKLGRKWIQLQGLFITGLMFAILAGSWDTISTGGRFACFVIAQFFSNFGPNATTFLYPAEVFPARVRGTAHGLSAALGKCGAILASLLFNFLTSVIGYGNVMWIFCGCMWGAIFFTLLLPETKMRDADEIDREEVLRGGNGKTHQGRWSWYFNGIF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	RLNPFSKSHSKNSNE CCCCCCCCCCCCCCC	31.62	25720772
12	Phosphorylation	NPFSKSHSKNSNENN CCCCCCCCCCCCCCC	40.39	25720772
15	Phosphorylation	SKSHSKNSNENNEVS CCCCCCCCCCCCCEE	49.62	28889911
22	Phosphorylation	SNENNEVSLADVAES CCCCCCEEHHHHHHH	16.20	25720772
29	Phosphorylation	SLADVAESDTRRHWL EHHHHHHHHHHHHHH	34.25	25720772
31	Phosphorylation	ADVAESDTRRHWLGL HHHHHHHHHHHHHCC	38.59	25720772
266	Phosphorylation	SKALNKYTDNDTYIA HHHHHHCCCCCCEEC	29.90	29996109
270	Phosphorylation	NKYTDNDTYIADDDE HHCCCCCCEECCCCC	24.07	24763107
294	Phosphorylation	EEKQINLTTSSDSHP CCEEEECCCCCCCCC	21.83	25720772
295	Phosphorylation	EKQINLTTSSDSHPT CEEEECCCCCCCCCC	29.42	29996109
296	Phosphorylation	KQINLTTSSDSHPTS EEEECCCCCCCCCCC	27.23	29996109
297	Phosphorylation	QINLTTSSDSHPTST EEECCCCCCCCCCCC	40.83	28889911
299	Phosphorylation	NLTTSSDSHPTSTED ECCCCCCCCCCCCCC	33.06	28889911
302	Phosphorylation	TSSDSHPTSTEDFGD CCCCCCCCCCCCCCC	42.74	24763107
303	Phosphorylation	SSDSHPTSTEDFGDK CCCCCCCCCCCCCCC	33.96	21712547
304	Phosphorylation	SDSHPTSTEDFGDKR CCCCCCCCCCCCCCC	41.89	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YAEC_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YAEC_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YAEC_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YAEC_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YAEC_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-297 AND SER-299, ANDMASS SPECTROMETRY.	18257517 [Abstract]