Y5098_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Y5098_DROME
• UniProt AC: Q6AWG9
• Protein Name: Uncharacterized protein CG5098
• Gene Name: CG5098
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 1238
• Protein Sequence: MNPLLAPPYSGTLPFNSMDLSLQSARSAAQPLAKQPPNQQPHQTQQQQQSLIHAPNYPSIQNLTTNATPTSTQLQQQQQQEHLAAMAAAHVSLLQSSRQNQGAPSGNLSNGGDCESLLPPPPPTSVSGNTNHTGSNSSSNSGSNNHIASPHYMQSRDENFKLTQLKRSFEPDLSGKNPQKEKDFGYPSASSASKLPTHNVQQQHANKKPSPLRNYHQQQQPPYNLTPKYNGPQTPPTPQSPLAANPHQMLSPTMDYNQLHLHHQLNSSSGGSYQHMQQDQTQSQSHPQHLHYHNQHATSQTAPPPLLPPLLTSGQFHAQPQDASQQQTASSSQHQTHHSRTAQLTNLDQAVKHKPESEEQPVITDLSYRNSETDKTAANPVPEAPESPYLTTSNEESLESNSNSSNSRKRRKRKASMVMRVTPNENAPEGENSKPQHPQQAANLNNSCSPKKSPKNGGGEFQPFSTQKQSQTENEKTTQENGRGGSPAPAENNSNSNSSTLYNDNENPKTKKQRQALLQRNLTEQHRMQQDDEPPKNHTSPAMPPPSPQSNSSSSSSSSSSANTHSSQSSHAVNNIPKPEINNKATTDTPASPALVEQGDIDAKPAVSVHECDEEEEPAVNKVSPAHPDPPTTAAVAAPPATESPKKSSPAANSESCPFGEVEDKLEQMFAGIEEETERISSPEKPAEESAAMVAHNLTAQLALDPSKTLDTPAENQTSVLAVLAPNQTPTPEIRPVATKAAMKSTMPSPVHSPIPQSRSTSTPLVAGDDSKSNTPVPAKAPAPRRPPPRRLSMGMDASLLRFMIDDPPAKKPGRKKKVTKEPDFEDDDKPSTSAAAAAALAARQLSEAASATKSKPAAGAKKKNAGVKGKKGSAGKGNAKNAKQNGKKSARKPAFTTDEDSTPAPTNGGGSVPELRFKSPFILIKPDGSVSIKNTHSAEDVNEKQTKVKKAPHERKNLRGMHSSTLSNRYDADTTDSTWICVFCKRGPHKLGLGDLFGPYLVTSDCDEYRAAVQTPGAQDIDGMFVNKRRREDMVKGQERNLPAVPATLANIMQAPKISMHKRKRKQTHDSSISYSDDPNESRSQCSSVDLLDCSTESKFVETFRGMGKTSENGFEVWLHEDCAVWSNDIHLIGAHVNGLDAAVWDSTRYQCVLCQQTGASICCFQRCCKAAAHVPCGRSANWSLSEEDRKVYCHLHRHEPGVVEPIKTESIAPVEVSVATPPAPAPPPAFNIHSLP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
416	Phosphorylation	KRRKRKASMVMRVTP HHHHHHHHEEEEECC	18.23	27626673
449	Phosphorylation	ANLNNSCSPKKSPKN HHCCCCCCCCCCCCC	39.31	29892262
453	Phosphorylation	NSCSPKKSPKNGGGE CCCCCCCCCCCCCCC	47.43	18327897
486	Phosphorylation	QENGRGGSPAPAENN CCCCCCCCCCCCCCC	22.25	22817900
642	Phosphorylation	AVAAPPATESPKKSS EEECCCCCCCCCCCC	42.65	22817900
644	Phosphorylation	AAPPATESPKKSSPA ECCCCCCCCCCCCCC	37.35	22668510
681	Phosphorylation	EEETERISSPEKPAE HHHHHHCCCCCCCHH	46.17	21082442
682	Phosphorylation	EETERISSPEKPAEE HHHHHCCCCCCCHHH	34.41	19060867
749	Phosphorylation	AMKSTMPSPVHSPIP HHHCCCCCCCCCCCC	28.82	22817900
753	Phosphorylation	TMPSPVHSPIPQSRS CCCCCCCCCCCCCCC	25.43	25749252
793	Phosphorylation	RPPPRRLSMGMDASL CCCCCCCCCCCCHHH	16.10	22817900
799	Phosphorylation	LSMGMDASLLRFMID CCCCCCHHHHHHHHC	24.54	22817900
1099	Phosphorylation	LLDCSTESKFVETFR EEECCCCHHHHHHHC	31.33	18327897

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Y5098_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Y5098_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Y5098_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of Y5098_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-453; THR-642; SER-682;SER-749; SER-753; SER-793; SER-799 AND SER-1099, AND MASSSPECTROMETRY.
PubMed: 18327897