Y4539_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Y4539_ARATH
• UniProt AC: Q9STJ8
• Protein Name: Receptor-like serine/threonine-protein kinase At4g25390
• Gene Name: At4g25390
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 651
• Subcellular Localization: Cell membrane; Single-pass type I membrane protein.
• Protein Sequence: MPSRSISAPVPVLAPAPIVSSLVPAAPSGHQNKTTRIFPPFVVAGAGAGFSLFITLSVCFCKFSRKRSSPPAENASSSPRRPSPREFSYSSLRRATGSFSQANRLGQGGFGVVFRGTISGGENVAVKVMDSGSLQGEGEFQNELFFAAKLDSPHVVPVIGFSHDRKRRRLLLVYKLMDNGNLQDALLHRRCPELMDWNRRFLVAVNIADGIKHLHSLEPPVIHGDIKPSNVLLDSLFSAKIADFGLARLKAEQVEISVAPERDGDGSMVEEVESVVTTVTGYEDFNFGLVDQSPESVAKVPGSVSASPEATTVVSVSPEMGEKTDEDGGSVVVMKKGKESESKDWWWKQESNVERGRVKEYVMQWIGSEVKKERPSRSDWIEAAALSSSSSKKLEKKTSKRLDWWLSLEEEDENKKKKKRRMVREWWKDEYRRELAKKRKKKKKMTLEAEFCSDDGSSSVSQWRRGSGSGSSIDWWLDGLSGERWLRARGNSHDSVSGEIAKSCGISSTPSMRGTVCYAAPEYCNLDNNVSEKCDVYSYGVLLLVLISGRRPLEMTGSASEIQRANLMSWARKLARRGKLVDLVDQKLQNLDQEQAVLCIKVALLCLQRLPISRPSMKEVLGMLKGEVNLPELPSEFSPSPPLKTTRKQRR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	N-linked_Glycosylation	AAPSGHQNKTTRIFP CCCCCCCCCCCCCCC	37.66	-
361	Phosphorylation	ERGRVKEYVMQWIGS CCHHHHHHHHHHHCH	8.77	19880383
368	Phosphorylation	YVMQWIGSEVKKERP HHHHHHCHHHHCCCC	30.04	19880383
391	Phosphorylation	AALSSSSSKKLEKKT HHHCCCCCHHHHHHH	35.44	17317660
467	Phosphorylation	VSQWRRGSGSGSSID HHHHCCCCCCCCCCC	28.16	23776212
469	Phosphorylation	QWRRGSGSGSSIDWW HHCCCCCCCCCCCHH	36.88	23776212
471	Phosphorylation	RRGSGSGSSIDWWLD CCCCCCCCCCCHHHC	26.31	23776212
472	Phosphorylation	RGSGSGSSIDWWLDG CCCCCCCCCCHHHCC	28.26	23776212
481	Phosphorylation	DWWLDGLSGERWLRA CHHHCCCCCCHHHHH	44.10	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Y4539_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Y4539_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Y4539_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of Y4539_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomics of early elicitor signaling inArabidopsis.";
Benschop J.J., Mohammed S., O'Flaherty M., Heck A.J.R., Slijper M.,Menke F.L.H.;
Mol. Cell. Proteomics 6:1198-1214(2007).
Cited for: PHOSPHORYLATION AT SER-391, IDENTIFICATION BY MASS SPECTROMETRY, ANDSUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
PubMed: 17317660