Y4245_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Y4245_ARATH
• UniProt AC: C0LGQ7
• Protein Name: Probable LRR receptor-like serine/threonine-protein kinase At4g20450
• Gene Name: At4g20450
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 898
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Sequence: MEGIHKLIFLALIWIFLITNIVDAQDQQGFISLDCGMPRNESSYTDESTGLNFSSDADFISSGKSGTIKTEDSDSGVKYIKPYKQLRYFPEGARNCYNLTVMQGTHYLIRAVFVYGNYDLKQRPKFDLYLGPNFWTTINLQDPSGGFYYRIWLQDGTVEEVIHMPKSNNLDICLVKTGTTTPFISSLELRPLRDDTYTTTTGSLKLISRWYFRKPFPTLESIIRHPDDVHDRLWDVYHADEEWTDINTTTPVNTTVNAFDLPQAIISKASIPQVASDTWSTTWSIQNPDDDVHVYLHFAEIQALKPSDTREFSILWNKNTIIRDYYSPLEFMADTVPIRTSSKCGDDGFCSLDLTRTKSSTLPPYCNAMEVFGLLQLLQTETDENDVTTLKNIQATYRIQKTNWQGDPCVPIQFIWTGLNCSNMFPSIPPRITSIDFSNFGLNGTITSDIQYLNQLQKLDLSNNNLTGKVPEFLAKMKLLTFINLSGNNLSGSIPQSLLNMEKNGLITLLYNGNNLCLDPSCESETGPGNNKKKLLVPILASAASVGIIIAVLLLVNILLLRKKKPSKASRSSMVANKRSYTYEEVAVITNNFERPLGEGGFGVVYHGNVNDNEQVAVKVLSESSAQGYKQFKAEVDLLLRVHHINLVTLVGYCDEGQHLVLIYEYMSNGNLKQHLSGENSRSPLSWENRLRIAAETAQGLEYLHIGCKPPMIHRDIKSMNILLDNNFQAKLGDFGLSRSFPVGSETHVSTNVAGSPGYLDPEYYRTNWLTEKSDVFSFGVVLLEIITSQPVIDQTREKSHIGEWVGFKLTNGDIKNIVDPSMNGDYDSSSLWKALELAMSCVSPSSSGRPNMSQVANELQECLLTENSRKGGRHDVDSKSSLEQSTSFGPEHIPDAR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	N-linked_Glycosylation	LDCGMPRNESSYTDE EECCCCCCCCCCCCC	47.86	-
52	N-linked_Glycosylation	TDESTGLNFSSDADF CCCCCCCCCCCCCCC	35.78	-
98	N-linked_Glycosylation	EGARNCYNLTVMQGT CCCCCCEEEEEECCC	31.28	-
247	N-linked_Glycosylation	DEEWTDINTTTPVNT CCCCCCCCCCCCCCC	33.90	-
253	N-linked_Glycosylation	INTTTPVNTTVNAFD CCCCCCCCCEECCCC	31.10	-
420	N-linked_Glycosylation	QFIWTGLNCSNMFPS EEEEECCCCCCCCCC	28.63	-
443	N-linked_Glycosylation	DFSNFGLNGTITSDI ECCCCCCCCCCCHHH	46.04	-
465	N-linked_Glycosylation	KLDLSNNNLTGKVPE CCCCCCCCCCCCHHH	43.14	-
484	N-linked_Glycosylation	MKLLTFINLSGNNLS CCHHHEEECCCCCCC	24.78	-
489	N-linked_Glycosylation	FINLSGNNLSGSIPQ EEECCCCCCCCCCCH	38.83	-
582	Phosphorylation	VANKRSYTYEEVAVI CCCCCCCCEEEEEEE	26.21	-
664	Phosphorylation	GQHLVLIYEYMSNGN CCEEEEEEEEHHCCC	9.24	-
750	Phosphorylation	VGSETHVSTNVAGSP CCCCEEEEECCCCCC	13.47	-
751	Phosphorylation	GSETHVSTNVAGSPG CCCEEEEECCCCCCC	32.40	-
764	Phosphorylation	PGYLDPEYYRTNWLT CCCCCHHHHCCCCCC	12.02	-
888	Phosphorylation	SSLEQSTSFGPEHIP CHHHHCCCCCCCCCC	33.19	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Y4245_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Y4245_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Y4245_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SERK2_ARATH	SERK2	physical	21423366
CNIH1_ARATH	AT3G12180	physical	24833385
VAP21_ARATH	AT5G47180	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.