dbPTM

Y3096_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	Y3096_DROME
UniProt AC	Q9VLK2
Protein Name	Ribosomal L1 domain-containing protein CG13096
Gene Name	CG13096
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	681
Subcellular Localization
Protein Description
Protein Sequence	MVKVQKPQPKSLNKSASIEGVVKKKGKPEKTKKLATDATLELASNKKAKNAAPVKKDAIKKEPEVSKKGAEKKQSKAAKRPLILAPPESPAAPAPAAKKSKAKPAASGAPVGKKIEAKKPLILAPPESPVPPKKQEKKTKAAPVKAKKEPAPAKKSVQDPVPSIKKVPAAKKSGQTAALTKKTAKTEKQAAPAKPAKAQPASQLQKKAKAVQKLSKPASPPKSKKALSKSKPGQAKGNAVNKEPAKSKKPVELTFELKAFDEKRFHEIVNENNVTKVCAALKSVVSEEVEKKKNTSIFSDYRYVLQVCSYKIPSCPKRMVKLNLKHSLVGKDDDVALIVPDLQRGAKFDYDPTKQHYEDMLREAGVKQRLTVVPFNQLRNEMGSFEAKRKFLNSYDYLLCDGRLSGQATAFLGKNTQKPRNVLHSLRLSKDNDKLPQEVTRALTRTAFRQLSKGDLIAVPVGNHEITAEQLAENILLVIKQLQEVYPGGLANIRSMYLKIDITGTSALPLYVSMCAPPEDVPYVVGPREQRMLKLKKQANEVLSKFAMTKDAEFIKLTSDQVKRKAQLRKEKAALLAADAAPKDNDGGDAAVPAKKARKESSSEGAKADAESDEEEEVEEAEDSAGESGDEDEEGHDGDDTDEDEDEDDDDDNEDGDDDEDEDDDEEDDDEEDDDDDDDEE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	QPKSLNKSASIEGVV CCCCCCCCCCCCHHH	26.61	25749252
17	Phosphorylation	KSLNKSASIEGVVKK CCCCCCCCCCHHHCC	28.41	19429919
89	Phosphorylation	LILAPPESPAAPAPA CEECCCCCCCCCCCH	26.13	19429919
128	Phosphorylation	LILAPPESPVPPKKQ EEECCCCCCCCCCCC	36.65	19429919
219	Phosphorylation	QKLSKPASPPKSKKA HHHCCCCCCCCCHHH	50.71	19429919
299	Phosphorylation	KKNTSIFSDYRYVLQ HCCCCCCCCHHHHHH	31.87	27626673
347	Acetylation	PDLQRGAKFDYDPTK CCCCCCCCCCCCCHH	41.41	21791702
429	Phosphorylation	VLHSLRLSKDNDKLP HHHHHHCCCCCCCCC	31.37	19429919
601	Phosphorylation	AKKARKESSSEGAKA HHHHHHHHCCHHHHC	42.05	19429919
602	Phosphorylation	KKARKESSSEGAKAD HHHHHHHCCHHHHCC	33.24	19429919
603	Phosphorylation	KARKESSSEGAKADA HHHHHHCCHHHHCCC	49.70	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of Y3096_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of Y3096_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of Y3096_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of Y3096_DROME

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos."; Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.; J. Proteome Res. 7:1675-1682(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-15 AND SER-17, AND MASSSPECTROMETRY.	18327897 [Abstract]
"An integrated chemical, mass spectrometric and computational strategyfor (quantitative) phosphoproteomics: application to Drosophilamelanogaster Kc167 cells."; Bodenmiller B., Mueller L.N., Pedrioli P.G.A., Pflieger D.,Juenger M.A., Eng J.K., Aebersold R., Tao W.A.; Mol. Biosyst. 3:275-286(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-89 AND SER-128, AND MASSSPECTROMETRY.	17372656 [Abstract]