dbPTM

Y1514_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	Y1514_ARATH
UniProt AC	Q9FRK5
Protein Name	Uncharacterized membrane protein At1g75140
Gene Name	At1g75140
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	617
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MADSQNGKSAFFFFFVSLILLFLSPSYSDVTASESDPIPYENSDASPGVVTSSESDRQGVSLHRLEELVRNLTELVARLDAKLSETPFKVKKEITRDEIEEKAKAFSVTKYSPFWSERFEFTSAVKLDSEATCINVLPFRDHEGLSKYFAVGDSSGRVFVFLRNGDVLVEFFTTCDSPITAMVSYMSVYKNESFVVTGHQSGVILLHRLREGSIGEDLNSAVMENVGKFDGTEDGLQVTLLEVHHVGRVRYILATDLSGKLTVFTENRTVYGSVSPTSRPLVFLKQRLLFLTETGAGSLDLRSMKIRESECEGLNHSLARSYVFDASERAKAYGFTSEGEIIHVLLLGDIMNFKCRVRSKKKVQMEEPVALQAIKGYLLIVNQEKVFVYNVSTQHYVRTTGPRLLFPAALEDIRSTFLSHRESTKTTDHQKLEKVTPLIASDREKLLVMGLGDGYVATYKSKLPISKAEFNTMLWSSPVFFFILFLFGAWHFFSKKKESLTAWGPDDPFSSTTMSSSSTTTAQNSSAFSESTRRNDDHMDLRRRYVSPSRYPPGAATGAYRSVGSNDPSSRAPVETTNYRTTAQEMKYRGGSGLDSGGFGKRRESLFGNNKALDDES

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
309	Phosphorylation	RSMKIRESECEGLNH HHCCCCHHHCCCCCH	37.38	30407730
317	Phosphorylation	ECEGLNHSLARSYVF HCCCCCHHHHHHHCC	23.73	30407730
545	Phosphorylation	HMDLRRRYVSPSRYP CCCHHHHHCCCCCCC	11.94	19376835
547	Phosphorylation	DLRRRYVSPSRYPPG CHHHHHCCCCCCCCC	14.28	30291188
549	Phosphorylation	RRRYVSPSRYPPGAA HHHHCCCCCCCCCCC	36.62	19376835
551	Phosphorylation	RYVSPSRYPPGAATG HHCCCCCCCCCCCCC	20.37	19376835
557	Phosphorylation	RYPPGAATGAYRSVG CCCCCCCCCCCCCCC	23.08	19376835
560	Phosphorylation	PGAATGAYRSVGSND CCCCCCCCCCCCCCC	12.55	23111157
565	Phosphorylation	GAYRSVGSNDPSSRA CCCCCCCCCCCCCCC	35.58	23111157
569	Phosphorylation	SVGSNDPSSRAPVET CCCCCCCCCCCCCCC	35.01	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of Y1514_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of Y1514_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of Y1514_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of Y1514_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of Y1514_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-547, AND MASSSPECTROMETRY.	19376835 [Abstract]