dbPTM

Y1385_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	Y1385_ARATH
UniProt AC	Q9CAJ9
Protein Name	BTB/POZ domain-containing protein At1g63850
Gene Name	At1g63850
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	548
Subcellular Localization
Protein Description	May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins..
Protein Sequence	MDYSTATTTAGNGYSSPRDSSFPSSFTKFNSALTAGLLNPMSPPPPPAMHDKTRSSPTLFEMMASEADTIGKVPVQIHNGVLPSPSSSSSSSSAAATAARTTNVNHLVISAQDKQALAMQRISDLLVIRSPGNQFNDPNSSDVKLTLSSKDGISITMCVHRQILVAHSRFFAMKLSDRWSKQQLPPSSSPYIVEISDCDDVEVYIETLMLMYCRDLRKKMMRHDVSRVLGILKVSAAIGFDAGVLSCLEYLEAAPWSEDEEYRIASLLSELHLENVGATEVLRRVSVEASNGNNGSNGGSNDEVLLNLLHIVLEGKDEKARRDMKTLVSKMLRENSSGNDLRKESLYLACDGCLHKLKRQFLQAAESDLENVDQIARQADNLHWILDILIDRQIAEDFIVMWASLSELSEVHSKVPVVHRFEISRVTARIFVGIGKGQILTPKEVRCLLLRNWLTPFYDDFGWMRRASKGLDRYLIEDGLSNTILTLPLAWQQEFFLAWFDRFLNSNEDCPNIQRGFEVWWRRAFWRRKEQSQEPARLRVTASATENS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
130	Phosphorylation	SDLLVIRSPGNQFND HHCEEEECCCCCCCC	26.49	30291188
140	Phosphorylation	NQFNDPNSSDVKLTL CCCCCCCCCCCEEEE	33.05	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of Y1385_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of Y1385_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of Y1385_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of Y1385_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of Y1385_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-130, AND MASSSPECTROMETRY.	19376835 [Abstract]