XPO2_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: XPO2_DROME
• UniProt AC: Q9XZU1
• Protein Name: Exportin-2
• Gene Name: Cse1 {ECO:0000312|FlyBase:FBgn0022213}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 975
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity)..
• Protein Sequence: MEVTEANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVAGAIAFKNYIKRNWAAHLDSDGPDRIHESDRNTIKTLIVTLMLHSPVALQKQLSDAVSIIGKYDFPKKWPQLIDEMVERFASGDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIKFVLDRMAKPLTDLLQAKMQLTKVHENNAGALKVIYGSLVLVNKVFFSLNSQDLPEFFEDNINTWMGAFIQQLAADVPSLRTADDEDAGVLEHLRAQVCENICLYAKKYDEEFKPFMEQFVTAVWELLVKTSLHTKYDSLVSHALQFLSVVADRQHYQSIFENPEILAQICDKVVIPNLDIRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAACDLVKTLSINFEQKIFGIFGQYLERLLTKYKENPATNWRSKDTAIYLVTSWASRGGTQKHGITQTSELVPLPEFCAQQIIPELERPNINEFPVLKAAAIKYVMVFRSILGPQVLASCLPQLIRHLPAESSVVHSYAACSVEKILSMRDASNAIVFGPQILAPYTTELISGLFATLSLPGSGENEYVMKAIMRSFSVLQSAAMPFMGVALPRLTEILTQVAKNPSRPQFNHYLFETLALCIKIVCHADSSAVSSFEEALFPVFQGILQQDIVEFMPYVFQMLSVLLEMREGTGTIPEPYWALFPCLLSPALWDRTGNVTPLIRLISAFIKQGSAQIQALGKLSGILGIFQKMIASKANDHEGFYLLQNLLSYYPPAEIQTNLRQIFGLLFQRLSLSKTPKYLSGIIIFFSFYVIKFSGSQMAQLIDEIQPNLFGMLLDRVFITEMGKIPKEQDRKMVAVGVTKLLTETPEILQQQYATFWPRLLHSLIDLFERPPEKLMGLEIGETAGVAEDPDAGYQVAFAQLTHAQPNQQDHLAEIKDARQFLATSLSKFAQARAGEFSTLLSPLEPEYKQVLQKYCDQAGVRIA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
411	Phosphorylation	IFGIFGQYLERLLTK HHHHHHHHHHHHHHH	15.77	19429919
417	Phosphorylation	QYLERLLTKYKENPA HHHHHHHHHHHHCCC	36.60	19429919
419	Phosphorylation	LERLLTKYKENPATN HHHHHHHHHHCCCCC	20.49	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of XPO2_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of XPO2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of XPO2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CPN_DROME	Cpn	physical	14605208
IMA_DROME	Pen	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.