| UniProt ID | XPO2_DANRE | |
|---|---|---|
| UniProt AC | Q7SZC2 | |
| Protein Name | Exportin-2 | |
| Gene Name | cse1l | |
| Organism | Danio rerio (Zebrafish) (Brachydanio rerio). | |
| Sequence Length | 971 | |
| Subcellular Localization |
Cytoplasm . Nucleus . Apical cell membrane Peripheral membrane protein . Basal cell membrane Peripheral membrane protein . Lateral cell membrane Peripheral membrane protein . Shuttles between the nucleus and the cytoplasm. |
|
| Protein Description | Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity). Negatively regulates fluid secretion and plays a role in fluid homeostasis by downregulating cftr activity. [PubMed: 20933420] | |
| Protein Sequence | MELNDGNLQTLTEYLQKTLSADPAVRRPAEKFLESVEGNQNYPILLLAVLEKSQNEVIRVCSAVTFKNYIKRNWRIVEDEPNKISDPDRTAIKANIVNLMLTSPEQIQKQLSDAISIIGREDFPLKWPDLLTEMVNRFQSGDFHIINGVLRTAHSLFKRYRHEFKSNELWSEIKLVLDTFAQPLTELFKATIELCQTHATDINALKVLFSSLTLISKLFYSLNFQDLPEFFEDNMETWMTNFHNLLTLDNKLLQTDDEEEAGLLELLKSQICDNAALYAQKYDEEFQPYLPRFVTAIWNLLVTTGQEVKYDLLVSNAIQFLASVCERPHYKHLFEDQNVLTSICEKVIVPNMEFRSADEEAFEDNSEEYIIRDLEGSDIDTRRRAACDLVRGLCKFFEGPVTGIFSGYVNSMLAEYAKNPGVNWKHKDAAIYLVTSLASKAQTQKHGITQANELVNLSEFFLNHILIDLKSPNVNEFPVLKSDAIKYVMTFRSQLPKEQLLQAVPLLVSHLQAESIVQHTYAAHALERLFTMRGGNNTTLITPTEMAPFTEQLLNHLFKALAIPGSSENEYIMKAIMRSFSLLQEAIVPYIPTLIGQLTHKLLLVSKNPSKPHFNHYLFESLCLSIRITCKANPDTVSSFEEALFPVFTEILQNDVQEFVPYVFQVMSLLLEIHSNSIPSSYMALFPHLLQPVLWERTGNIPPLVRLLQAYLEKGAAAIANTASDKIPGLLGVFQKLIASKANDHQGFYLLNSIVEHMPAEAITQYRKQIFILLFQRLQSSKTTKFVKSFLVFINLYSVKYGAIALQEIFDDIQPKMFGMVVEKIVIPEVQKVSGQVEKKICAVGIIKILTECPAMMDTEYTKLWAPLLQALIGLFELPEDDSIPDDEHFIDIEDTPGYQTAFSQLAFAGKKEHDPIGDAVSNPKILLAQSLHKLSTACPGRVPSMLSTSLPTEALQFLQGYLQAATVQLV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of XPO2_DANRE !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of XPO2_DANRE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of XPO2_DANRE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of XPO2_DANRE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of XPO2_DANRE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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