XKR6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: XKR6_HUMAN
• UniProt AC: Q5GH73
• Protein Name: XK-related protein 6
• Gene Name: XKR6
• Organism: Homo sapiens (Human).
• Sequence Length: 641
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MAAKSDGGGVGVGFAQLHNLDEAVGSGGEEDGEPGGGGCGGGGDGSEPGESSSMHICHCCNTSSCYWGCRSACLRSLLGRKPRRSAAADGGDQPLQPPAAPGAGRQPPTPSAARPEPPPPQVERPWLDCLWIVLALLVFFGDVGTDLWLALDYYRKGDYVYFGLTLFFVLVPSLLVQSLSFRWFVQDYTGGGLGAVEGLTSRGPPMMGAGYVHGAARGGPGVRVSPTPGAQRLCRLSVWIWQSVIHLLQMGQVWRYIRTMYLGIQSQRRKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLYIMLQKNSAETLPCVSSVTSLMSLAWVLASYHKLLRDSRDDKKSMSYRGAIIQVFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRDPETTDSYAVPALCCVFISFVAGIAMMLLYYGVLHPTGPRAKILASSCCAELLWGIPLPPDVEPMAPEIPGYRGTQVTPTRAVTEQQEDLTADTCLPVFQVRPMGPPTPLGRPYLPEGPLIKIDMPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
71	Phosphorylation	SCYWGCRSACLRSLL CCHHHHHHHHHHHHH	27.66	24719451
180	Phosphorylation	SLLVQSLSFRWFVQD HHHHHHCCHHHHHCC	20.29	24719451
211	Phosphorylation	PPMMGAGYVHGAARG CCCCCCCCCCCCCCC	6.69	-
277	Phosphorylation	KEHQRRFYWAMMYEY HHHHHHHHHHHHHHH	7.17	-
282	Phosphorylation	RFYWAMMYEYADVNM HHHHHHHHHHCCHHH	7.84	24043423
284	Phosphorylation	YWAMMYEYADVNMLR HHHHHHHHCCHHHHH	7.21	26552605
295	Phosphorylation	NMLRLLETFLESAPQ HHHHHHHHHHHHHHH	33.23	24043423
299	Phosphorylation	LLETFLESAPQLVLQ HHHHHHHHHHHHHHH	47.61	24043423
308	Phosphorylation	PQLVLQLYIMLQKNS HHHHHHHHHHHHCCC	3.26	24043423
315	Phosphorylation	YIMLQKNSAETLPCV HHHHHCCCCCCCCCC	34.22	25002506
318	Phosphorylation	LQKNSAETLPCVSSV HHCCCCCCCCCCHHH	35.40	25002506
323	Phosphorylation	AETLPCVSSVTSLMS CCCCCCCHHHHHHHH	26.30	25002506
324	Phosphorylation	ETLPCVSSVTSLMSL CCCCCCHHHHHHHHH	14.71	25002506
326	Phosphorylation	LPCVSSVTSLMSLAW CCCCHHHHHHHHHHH	20.35	25002506
327	Phosphorylation	PCVSSVTSLMSLAWV CCCHHHHHHHHHHHH	21.66	25002506
330	Phosphorylation	SSVTSLMSLAWVLAS HHHHHHHHHHHHHHH	21.89	25002506
337	Phosphorylation	SLAWVLASYHKLLRD HHHHHHHHHHHHHHC	24.49	25002506
338	Phosphorylation	LAWVLASYHKLLRDS HHHHHHHHHHHHHCC	9.43	25002506
471	Phosphorylation	RDPETTDSYAVPALC CCCCCCCCCHHHHHH	16.95	24275569
472	Phosphorylation	DPETTDSYAVPALCC CCCCCCCCHHHHHHH	17.90	24275569
483	Phosphorylation	ALCCVFISFVAGIAM HHHHHHHHHHHHHHH	11.38	24275569
494	Phosphorylation	GIAMMLLYYGVLHPT HHHHHHHHHHHHCCC	8.33	24275569
495	Phosphorylation	IAMMLLYYGVLHPTG HHHHHHHHHHHCCCC	10.75	24275569
501	Phosphorylation	YYGVLHPTGPRAKIL HHHHHCCCCHHHHHH	49.42	24275569
544	Phosphorylation	RGTQVTPTRAVTEQQ CCCCCCCCCCCCCCC	23.15	-
578	Phosphorylation	PTPLGRPYLPEGPLI CCCCCCCCCCCCCEE	33.26	-
609	Phosphorylation	VDRRLRRTINILQYV HHHHHHHHHHHHHHH	16.37	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of XKR6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of XKR6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of XKR6_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of XKR6_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.