XKR3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: XKR3_HUMAN
• UniProt AC: Q5GH77
• Protein Name: XK-related protein 3
• Gene Name: XKR3
• Organism: Homo sapiens (Human).
• Sequence Length: 459
• Subcellular Localization: Cell membrane ; Multi-pass membrane protein .
• Protein Sequence: METVFEEMDEESTGGVSSSKEEIVLGQRLHLSFPFSIIFSTVLYCGEVAFGLYMFEIYRKANDTFWMSFTISFIIVGAILDQIILMFFNKDLRRNKAALLFWHILLLGPIVRCLHTIRNYHKWLKNLKQEKEETQVSITKRNTMLEREIAFSIRDNFMQQKAFKYMSVIQAFLGSVPQLILQMYISLTIREWPLNRALLMTFSLLSVTYGAIRCNILAIQISNDDTTIKLPPIEFFCVVMWRFLEVISRVVTLAFFIASLKLKSLPVLLIIYFVSLLAPWLEFWKSGAHLPGNKENNSNMVGTVLMLFLITLLYAAINFSCWSAVKLQLSDDKIIDGRQRWGHRILHYSFQFLENVIMILVFRFFGGKTLLNCCDSLIAVQLIISYLLATGFMLLFYQYLYPWQSGKVLPGRTENQPEAPYYYVNIEKTEKNKNKQLRNYCHSCNRVGYFSIRKSMTCS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
152	Phosphorylation	LEREIAFSIRDNFMQ HHHHHHHHHHHHHHH	14.00	24043423
165	Phosphorylation	MQQKAFKYMSVIQAF HHHHHHHHHHHHHHH	6.54	22210691
167	Phosphorylation	QKAFKYMSVIQAFLG HHHHHHHHHHHHHHC	16.99	26074081
175	Phosphorylation	VIQAFLGSVPQLILQ HHHHHHCCHHHHHHH	32.54	26074081
184	Phosphorylation	PQLILQMYISLTIRE HHHHHHHHHHHHHHC	3.71	24043423
186	Phosphorylation	LILQMYISLTIREWP HHHHHHHHHHHHCCC	11.28	24043423
188	Phosphorylation	LQMYISLTIREWPLN HHHHHHHHHHCCCCH	15.93	22210691
298	Phosphorylation	PGNKENNSNMVGTVL CCCCCCCCCHHHHHH	37.57	24905233
303	Phosphorylation	NNSNMVGTVLMLFLI CCCCHHHHHHHHHHH	10.08	24905233
311	Phosphorylation	VLMLFLITLLYAAIN HHHHHHHHHHHHHHH	16.92	24905233
314	Phosphorylation	LFLITLLYAAINFSC HHHHHHHHHHHHHHH	9.33	24905233
320	Phosphorylation	LYAAINFSCWSAVKL HHHHHHHHHHHHHHC	15.36	24905233
323	Phosphorylation	AINFSCWSAVKLQLS HHHHHHHHHHHCCCC	27.75	24905233
457	Phosphorylation	FSIRKSMTCS----- EEEECCCCCC-----	19.38	-
459	Phosphorylation	IRKSMTCS------- EECCCCCC-------	33.81	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of XKR3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of XKR3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of XKR3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of XKR3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.