WUN_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: WUN_DROME
• UniProt AC: Q9V576
• Protein Name: Putative phosphatidate phosphatase
• Gene Name: wun
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 379
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: Responsible for guiding the germ cells early in the process of migration from the lumen of the developing gut towards the overlying mesoderm, where the germ cells enter the gonads. May be involved in lipid metabolism..
• Protein Sequence: MPAVKIIMSTETSASETTPLRRSENETPDHKELAQSNSNSRQTTVNSNNNNYSNSVQVRLQEQDRDSDSEQQQHTATITMDTNKRILCRVGLDVLILLCAGFPILLFFLLGEPYKRGFFCDDESLKHPFHDSTVRNWMLYFIGAVIPVGVIFIVEVIISQNKAKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQLTTDIAKYSIGRLRPHFIAVCQPQMADGSTCDDAINAGKYIQEFTCKGVGSSARMLKEMRLSFPSGHSSFTFFAMVYLALYLQARMTWRGSKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSLIGSISALVVANYVSDLFQKPNTKPYLARTVQDMNASPAQAITITTN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	N-linked_Glycosylation	TVNSNNNNYSNSVQV EECCCCCCCCCCEEE	43.67	-
67	Phosphorylation	LQEQDRDSDSEQQQH EEECCCCCCHHHHHE	43.88	22668510
169	N-linked_Glycosylation	KAKQDNGNATSRRYV HHCCCCCCCCCCEEE	46.42	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of WUN_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of WUN_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of WUN_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of WUN_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.