dbPTM

WSC1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	WSC1_SCHPO
UniProt AC	P87179
Protein Name	Cell wall integrity and stress response component 1
Gene Name	wsc1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	374
Subcellular Localization	Membrane Single-pass membrane protein .
Protein Description
Protein Sequence	MVFLNSSPFKGRLLFFVYLLIISTRLVAADMNTQYGCYLVDSSLTEQGTFTYLDPAYCYNNICGGSDNIAFVAIRNNQCYCGSTLTATEVSSSLCTTPCPGYGSLMCGGDLYWSVYLTGNGVLQTTVSSSSVSSTTSSSSSSSPSSSSTTTTTSPSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSVPITSSTSSSHSSSSSSSSSSSSSSRPSSSSSFITTMSSSTFISTVTVTPSSSSSSTSSEVPSSTAALALNASKASNHTSLNAGAIVGIVIGCVAFAVVMALCIFLYFYFRRFKIRMSDSANEGKYPSYASELDSRLDPAMMNRKSSESLADSQDYSRKILRVTNLN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
278	N-linked_Glycosylation	STAALALNASKASNH HHHHHHHCHHHHCCC	36.24	-
284	N-linked_Glycosylation	LNASKASNHTSLNAG HCHHHHCCCCCCCHH	47.52	-
327	Phosphorylation	FKIRMSDSANEGKYP HCEECCCCCCCCCCC	26.20	25720772
335	Phosphorylation	ANEGKYPSYASELDS CCCCCCCHHHHHHHH	30.18	25720772
336	Phosphorylation	NEGKYPSYASELDSR CCCCCCHHHHHHHHH	15.05	25720772
338	Phosphorylation	GKYPSYASELDSRLD CCCCHHHHHHHHHCC	30.38	25720772
353	Phosphorylation	PAMMNRKSSESLADS HHHHCCCCCHHHCCC	35.78	24763107
354	Phosphorylation	AMMNRKSSESLADSQ HHHCCCCCHHHCCCH	33.95	28889911
356	Phosphorylation	MNRKSSESLADSQDY HCCCCCHHHCCCHHH	30.70	24763107
360	Phosphorylation	SSESLADSQDYSRKI CCHHHCCCHHHHHHH	21.24	25720772
364	Phosphorylation	LADSQDYSRKILRVT HCCCHHHHHHHHHHH	35.07	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of WSC1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of WSC1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of WSC1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of WSC1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of WSC1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-354, AND MASSSPECTROMETRY.	18257517 [Abstract]