| UniProt ID | WNT8A_HUMAN | |
|---|---|---|
| UniProt AC | Q9H1J5 | |
| Protein Name | Protein Wnt-8a | |
| Gene Name | WNT8A | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 351 | |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix . Secreted . | |
| Protein Description | Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning.. | |
| Protein Sequence | MGNLFMLWAALGICCAAFSASAWSVNNFLITGPKAYLTYTTSVALGAQSGIEECKFQFAWERWNCPENALQLSTHNRLRSATRETSFIHAISSAGVMYIITKNCSMGDFENCGCDGSNNGKTGGHGWIWGGCSDNVEFGERISKLFVDSLEKGKDARALMNLHNNRAGRLAVRATMKRTCKCHGISGSCSIQTCWLQLAEFREMGDYLKAKYDQALKIEMDKRQLRAGNSAEGHWVPAEAFLPSAEAELIFLEESPDYCTCNSSLGIYGTEGRECLQNSHNTSRWERRSCGRLCTECGLQVEERKTEVISSCNCKFQWCCTVKCDQCRHVVSKYYCARSPGSAQSLGKGSA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 98 | Phosphorylation | ISSAGVMYIITKNCS HHHCCEEEEEECCCC | 6.17 | 29116813 | |
| 103 | N-linked_Glycosylation | VMYIITKNCSMGDFE EEEEEECCCCCCCCC | 17.91 | UniProtKB CARBOHYD | |
| 105 | Phosphorylation | YIITKNCSMGDFENC EEEECCCCCCCCCCC | 34.88 | - | |
| 117 | Phosphorylation | ENCGCDGSNNGKTGG CCCCCCCCCCCCCCC | 17.55 | - | |
| 186 | O-palmitoleoylation | TCKCHGISGSCSIQT HCCCCCCCCCCCEEE | 29.28 | - | |
| 193 | Phosphorylation | SGSCSIQTCWLQLAE CCCCCEEEHHHHHHH | 12.18 | 24719451 | |
| 207 | Phosphorylation | EFREMGDYLKAKYDQ HHHHHHHHHHHHHHH | 12.36 | - | |
| 262 | N-linked_Glycosylation | SPDYCTCNSSLGIYG CCCCCCCCCCCCEEC | 19.24 | UniProtKB CARBOHYD | |
| 281 | N-linked_Glycosylation | ECLQNSHNTSRWERR HHHHCCCCCCHHHHH | 39.30 | UniProtKB CARBOHYD | |
| 339 | Phosphorylation | SKYYCARSPGSAQSL EHHEECCCCCCHHHC | 18.32 | - | |
| 342 | Phosphorylation | YCARSPGSAQSLGKG EECCCCCCHHHCCCC | 26.90 | - | |
| 345 | Phosphorylation | RSPGSAQSLGKGSA- CCCCCHHHCCCCCC- | 38.51 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of WNT8A_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of WNT8A_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of WNT8A_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of WNT8A_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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