WNT7A_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: WNT7A_MOUSE
• UniProt AC: P24383
• Protein Name: Protein Wnt-7a
• Gene Name: Wnt7a
• Organism: Mus musculus (Mouse).
• Sequence Length: 349
• Subcellular Localization: Secreted, extracellular space, extracellular matrix . Secreted .
• Protein Description: Ligand for members of the frizzled family of seven transmembrane receptors. [PubMed: 18230341]
• Protein Sequence: MTRKARRCLGHLFLSLGIVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
83	N-linked_Glycosylation	QFRNGRWNCSALGER EECCCCCCCCCCCCE	14.43	-
127	N-linked_Glycosylation	TAACTQGNLSDCGCD HHHHHCCCHHHCCCC	26.93	-
206	O-palmitoleoylation	ECKCHGVSGSCTTKT EEEEECCCCCCCCCC	29.58	-
295	N-linked_Glycosylation	GTQGRACNKTAPQAS CCCCCCCCCCCCCCC	43.67	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of WNT7A_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of WNT7A_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of WNT7A_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DVL1_MOUSE	Dvl1	genetic	16818724
DKK1_MOUSE	Dkk1	genetic	15242796

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.