dbPTM

WLI2B_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	WLI2B_ARATH
UniProt AC	Q9M047
Protein Name	LIM domain-containing protein WLIM2b {ECO:0000305}
Gene Name	WLIM2B {ECO:0000303\|PubMed:17573466}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	199
Subcellular Localization	Cytoplasm, cytoskeleton .
Protein Description	Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are not regulated by pH and [Ca(2+)]..
Protein Sequence	MSFTGTQQKCKACEKTVYAVELLSADGVGYHKSCFKCTHCKSRLQLSSYSSMEGVLYCKPHFEQLFKESGSFNKNFQSPAKSADKSTPELTRTPSRVAGRFSGTQEKCATCSKTVYPIEKVTVESQTYHKSCFKCSHGGCPISPSNYAALEGILYCKHHFAQLFKEKGSYNHLIKSASIKRSAAAAVAAGVPAASVPES

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
2	Phosphorylation	------MSFTGTQQK ------CCCCCCHHH	25561503
4	Phosphorylation	----MSFTGTQQKCK ----CCCCCCHHHHH	25561503
6	Phosphorylation	--MSFTGTQQKCKAC --CCCCCCHHHHHHC	25561503
42	Phosphorylation	FKCTHCKSRLQLSSY HCCCCCCCCEECCCC	23572148
71	Phosphorylation	QLFKESGSFNKNFQS HHHHHHCCCCCCCCC	30407730
78	Phosphorylation	SFNKNFQSPAKSADK CCCCCCCCCCCCCCC	19880383
82	Phosphorylation	NFQSPAKSADKSTPE CCCCCCCCCCCCCCC	19880383
91	Phosphorylation	DKSTPELTRTPSRVA CCCCCCCCCCHHHHC	29654922
93	Phosphorylation	STPELTRTPSRVAGR CCCCCCCCHHHHCCC	30407730
95	Phosphorylation	PELTRTPSRVAGRFS CCCCCCHHHHCCCCC	19880383
169	Phosphorylation	QLFKEKGSYNHLIKS HHHHHHCCHHHHHHH	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of WLI2B_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of WLI2B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of WLI2B_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of WLI2B_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of WLI2B_ARATH

Related Literatures of Post-Translational Modification