WIPI3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: WIPI3_MOUSE
• UniProt AC: Q9CR39
• Protein Name: WD repeat domain phosphoinositide-interacting protein 3
• Gene Name: Wdr45b
• Organism: Mus musculus (Mouse).
• Sequence Length: 344
• Protein Sequence: MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFSPKGECVRDVCAQFLEMTDDKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
206	Ubiquitination	RIATASEKGTLIRIF EEEEECCCCCEEEEE	55.49	27667366
266	Ubiquitination	AEDPKRNKQSSLASA ECCCCCCCCCCHHCH	56.44	27667366
272	Phosphorylation	NKQSSLASASFLPKY CCCCCHHCHHHCHHH	29.73	-
325	Ubiquitination	YKFLFSPKGECVRDV EEEEECCCCHHHHHH	67.17	-
340	Phosphorylation	CAQFLEMTDDKL--- HHHHHHHCCCCC---	31.50	28576409

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of WIPI3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of WIPI3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of WIPI3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of WIPI3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.