WIPF3_HUMAN - dbPTM
WIPF3_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID WIPF3_HUMAN
UniProt AC A6NGB9
Protein Name WAS/WASL-interacting protein family member 3
Gene Name WIPF3
Organism Homo sapiens (Human).
Sequence Length 483
Subcellular Localization Cytoplasm. In hippocampal neurons colocalizes with WASL in the cell body, axons and the growth cone..
Protein Description May be a regulator of cytoskeletal organization. May have a role in spermatogenesis (By similarity)..
Protein Sequence MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPWLQAEAVGQSSDDIKGRNSQLSLKTLR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
44UbiquitinationSLRRADPKGRSALLA
HHHHCCCCCHHHHHH		68.45-
46Asymmetric dimethylarginineRRADPKGRSALLADI
HHCCCCCHHHHHHHH		25.53-
46MethylationRRADPKGRSALLADI
HHCCCCCHHHHHHHH		25.5324129315
93PhosphorylationSANTRGASTPPTLGD
CCCCCCCCCCCCHHH		44.2526434776
94PhosphorylationANTRGASTPPTLGDL
CCCCCCCCCCCHHHH		32.5226434776
97PhosphorylationRGASTPPTLGDLFAG
CCCCCCCCHHHHHHC		44.5728348404
122PhosphorylationRDVAGGKTGQGPGSR
CCCCCCCCCCCCCCC		37.7026434776
128PhosphorylationKTGQGPGSRAPSPRL
CCCCCCCCCCCCCCC		28.5326434776
132PhosphorylationGPGSRAPSPRLPNKT
CCCCCCCCCCCCCCC		22.9726434776
139PhosphorylationSPRLPNKTISGPLIP
CCCCCCCCCCCCCCC		27.3226437602
141PhosphorylationRLPNKTISGPLIPPA
CCCCCCCCCCCCCCC		39.3223186163
149PhosphorylationGPLIPPASPRLGNTS
CCCCCCCCCCCCCCC		19.1422617229
155PhosphorylationASPRLGNTSEAHGAA
CCCCCCCCCHHCCCC		26.58-
156PhosphorylationSPRLGNTSEAHGAAR
CCCCCCCCHHCCCCC		36.46-
192PhosphorylationPLPPPLPSSSPIKTP
CCCCCCCCCCCCCCC		51.6523186163
193PhosphorylationLPPPLPSSSPIKTPL
CCCCCCCCCCCCCCC		37.8923186163
194PhosphorylationPPPLPSSSPIKTPLV
CCCCCCCCCCCCCCC		34.6723186163
202PhosphorylationPIKTPLVSPPGPLTK
CCCCCCCCCCCCCCC		32.8128348404
208PhosphorylationVSPPGPLTKGNLPVV
CCCCCCCCCCCCCCC		39.7923186163
233PhosphorylationPPPPPPPTPPPLPPA
CCCCCCCCCCCCCCH		54.9526657352
281PhosphorylationGLKAEPASPAQDAQE
CCCCCCCCCCCCCCC		31.3326657352
299PhosphorylationPPPPLPPYASCSPRA
CCCCCCCCCCCCCCC		14.8126657352
318PhosphorylationPPLPGVNSSSETPPP
CCCCCCCCCCCCCCC		32.6027251275
319PhosphorylationPLPGVNSSSETPPPL
CCCCCCCCCCCCCCC		27.3027251275
320PhosphorylationLPGVNSSSETPPPLP
CCCCCCCCCCCCCCC		45.3626657352
322PhosphorylationGVNSSSETPPPLPPK
CCCCCCCCCCCCCCC		42.9427251275
330PhosphorylationPPPLPPKSPSFQAPP
CCCCCCCCCCCCCCC		31.3926657352
332PhosphorylationPLPPKSPSFQAPPQK
CCCCCCCCCCCCCCC		36.7624275569
383PhosphorylationPPAPPARSPTTELSS
CCCCCCCCCCCCCCC		28.8028348404
385PhosphorylationAPPARSPTTELSSKS
CCCCCCCCCCCCCHH		33.8628857561
386PhosphorylationPPARSPTTELSSKSQ
CCCCCCCCCCCCHHH		38.0127050516
389PhosphorylationRSPTTELSSKSQQAT
CCCCCCCCCHHHCCC		29.5028857561
390PhosphorylationSPTTELSSKSQQATA
CCCCCCCCHHHCCCC		49.2928857561
392PhosphorylationTTELSSKSQQATAWT
CCCCCCHHHCCCCCC		29.4927174698
396PhosphorylationSSKSQQATAWTPTQQ
CCHHHCCCCCCCCCC		20.5627174698
399PhosphorylationSQQATAWTPTQQPGG
HHCCCCCCCCCCCCC		17.6227174698
401PhosphorylationQATAWTPTQQPGGQL
CCCCCCCCCCCCCCC		32.2527174698
412PhosphorylationGGQLRNGSLHIIDDF
CCCCCCCEEEEEECC		21.9626434776
437PhosphorylationDFPPPDEYKPCQKIY
CCCCCCCCCCCCCCC		27.8426074081
444PhosphorylationYKPCQKIYPSKIPRS
CCCCCCCCCCCCCCC		14.4326074081
446PhosphorylationPCQKIYPSKIPRSRT
CCCCCCCCCCCCCCC		26.6726074081
451PhosphorylationYPSKIPRSRTPGPWL
CCCCCCCCCCCCCCE		34.8426074081
453PhosphorylationSKIPRSRTPGPWLQA
CCCCCCCCCCCCEEE		33.5727422710
466PhosphorylationQAEAVGQSSDDIKGR
EEEECCCCCCCCCCC		29.7926074081
467PhosphorylationAEAVGQSSDDIKGRN
EEECCCCCCCCCCCC		31.2626074081
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of WIPF3_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of WIPF3_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of WIPF3_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of WIPF3_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of WIPF3_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory