| UniProt ID | WIP1_ARATH | |
|---|---|---|
| UniProt AC | Q8GXA4 | |
| Protein Name | WPP domain-interacting protein 1 | |
| Gene Name | WIP1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 489 | |
| Subcellular Localization |
Nucleus envelope . Nucleus membrane Single-pass membrane protein Cytoplasmic side . Targeted to the nuclear envelope (NE) during interphase. Associated to the cell plate during cytokinesis in root tips. |
|
| Protein Description | Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips. [PubMed: 17600715] | |
| Protein Sequence | MDLESESSALESVDDNVLIQQSASNVCDDGRSLDNGSCSDESVKLLSTSNSVELGKPMSFDSPGDGGGAYSPVLKGQGLRKWRRIRRDLVKDTSANMENSKALKRGLSGVAHSHGKQMQFQSPEVEQESQGSVGSVNMLKSSGDGFDILGSSGYDSRFVAGVGFSAGMDLEIDDDRSSKSSTVARAPKVIRYEKPMISSGQGGNIRVENSKKHRGESVDFEKENSYSSLESDSRKQSGRMMDYNGENGETSMRKDDAGGEGGESINTDNRYSDEMDPLTEAINGFLALQDALEKEVQQFQEIGNEPMPQHHEQVSEANSPHPEIVTLVNNVEQLENMLEETRSMLEVKESHIRDLESTTNQSKHSWGGTEIVVEDIFRQKIEAEIEYLIYSRSIDNLNSQMKLIDEQESLAEEQTHETLNKLGRVQTKAANFTNRAQDLQNDCIEITGTIKKRACKITSYVLIQLVLLSTVVLLLLSQLLPEPDTVVPT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 62 | Phosphorylation | GKPMSFDSPGDGGGA CCCCCCCCCCCCCCC | 28.86 | 27288362 | |
| 70 | Phosphorylation | PGDGGGAYSPVLKGQ CCCCCCCCCCHHCCC | 19.44 | 27288362 | |
| 71 | Phosphorylation | GDGGGAYSPVLKGQG CCCCCCCCCHHCCCC | 14.16 | 27288362 | |
| 108 | Phosphorylation | KALKRGLSGVAHSHG HHHHHHHHHCHHCCC | 33.76 | 23111157 | |
| 182 | Phosphorylation | DRSSKSSTVARAPKV CCCCCCHHHHCCCCE | 25.85 | 19880383 | |
| 217 | Phosphorylation | SKKHRGESVDFEKEN CCCCCCCCCCCCCCC | 29.79 | 25561503 | |
| 225 | Phosphorylation | VDFEKENSYSSLESD CCCCCCCCCCCCCCC | 27.73 | 30407730 | |
| 226 | Phosphorylation | DFEKENSYSSLESDS CCCCCCCCCCCCCCC | 17.54 | 30407730 | |
| 227 | Phosphorylation | FEKENSYSSLESDSR CCCCCCCCCCCCCCC | 28.41 | 30407730 | |
| 228 | Phosphorylation | EKENSYSSLESDSRK CCCCCCCCCCCCCCC | 28.11 | 30407730 | |
| 231 | Phosphorylation | NSYSSLESDSRKQSG CCCCCCCCCCCCCCC | 46.29 | 30407730 | |
| 233 | Phosphorylation | YSSLESDSRKQSGRM CCCCCCCCCCCCCCC | 51.13 | 30407730 | |
| 264 | Phosphorylation | AGGEGGESINTDNRY CCCCCCCCCCCCCCC | 25.14 | 30407730 | |
| 267 | Phosphorylation | EGGESINTDNRYSDE CCCCCCCCCCCCCCC | 32.74 | 30407730 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of WIP1_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of WIP1_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of WIP1_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-182, AND MASSSPECTROMETRY. | |
