dbPTM

WDR48_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	WDR48_CAEEL
UniProt AC	Q20059
Protein Name	WD repeat-containing protein 48 homolog
Gene Name	wdr-48
Organism	Caenorhabditis elegans.
Sequence Length	683
Subcellular Localization
Protein Description	Together with wdr-20, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor..
Protein Sequence	MSSCVNTSQTGPKKKISFIIRDEHEYSNRSAVSALQYDAQNGRLFTGGSDTIIRTWSVPHHKDAFSARGGVRSPGKNSPVQYQGSLEQHTDWVNDMILCGHGKILISASNDTTVKVWNIERDNKHGFIDCIRTHKDYVSCLAYAPIVEKAVSASFDHNIFVYDINANFKTVNNLIGCKDSIYSLATTPNLSLVLGAGTEKCIRLFDPRTNEKIMKLRGHTDNVRALVVNDDGTRALSAGSDATIRLWDIGQQRCIATCIAHEEGVWTLQVDSSFTTVYSAGKDKMVVKTPLYDFTKSQLLFKEEAPVKKLLLSEKDNPVSLWVGTWKSDIKRWSIRPSAQLSIGGDEDGPSTSNANHSVSASSSPPVTFKYIRVKDQKGQQSTPELVIPGAPAIKKHAMLSDKRHVLTRDSDGNVALYDVLAARKIKDYGKRIFEEVVDENSRQVYIPSWFVVDSKSGMLQITLDELDALSSWLSSKDAGFDDNDRETKLNYGGMMLRSLFERWPPCKMTNVDAADADDVQKATLNFISLPEHTPLIICEGNGRPLYRLLVGDAGKEFEANELAQIAPMWVIDAIERNQLPKFNKMPFYLLPHPSTNPKQPKKDRLSATEMLQVKKVMEHVYEKILSTNDDITVGSIPLNQIHTKMEMYCNDQRLEPDMDLRTVKHLYWKQSGELLLHYKPVK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
73	Phosphorylation	SARGGVRSPGKNSPV CCCCCCCCCCCCCCC	35.28	19530675

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of WDR48_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of WDR48_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of WDR48_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of WDR48_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of WDR48_CAEEL

Related Literatures of Post-Translational Modification