WDR47_MOUSE - dbPTM
WDR47_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID WDR47_MOUSE
UniProt AC Q8CGF6
Protein Name WD repeat-containing protein 47
Gene Name Wdr47
Organism Mus musculus (Mouse).
Sequence Length 920
Subcellular Localization Cytoplasm, cytoskeleton . Localization along microtubules is mediated by MAP1S.
Protein Description
Protein Sequence MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQHLEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEVCVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIYEESPERSDTPVEAQQPVSSEAMCQGSGLEKEPANGAQNPVPAKQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQMYQQMLLEGGVNQEDGPDQQQNLTEQFLNRSIQKLGELNIGMDSLGNEVPVLNQQCSGSKNNGSNNSSVTSFSTPPQDSSQRLIHDTANIHTSTPRNPGSTNHIPFHEDSPCGSQNSSEHSVIKPSPGDSSGNLSRSKGEEDDKSKKQFVCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYSG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MTAEETVNV
------CCHHHCCCH		42.6628576409
25UbiquitinationILDFLNSKKLHISML
HHHHHCCCCCEEEEH		59.2822790023
102PhosphorylationLCVNNAMSAEDEPQH
HHHHCCCCCCCCCHH		26.54-
183PhosphorylationIPADRKLSEAGFKAS
CCCCCHHHHCCCCCC		28.5628066266
188UbiquitinationKLSEAGFKASNNRLF
HHHHCCCCCCCCHHH		50.4122790023
195UbiquitinationKASNNRLFQLVMKGL
CCCCCHHHHHHHHHH		4.8227667366
280PhosphorylationLKPTKAAYADLLTPL
CCCCHHHHHHHHHHH		12.9029899451
285PhosphorylationAAYADLLTPLISKLS
HHHHHHHHHHHHHCC		24.2822324799
289PhosphorylationDLLTPLISKLSPYPS
HHHHHHHHHCCCCCC		34.9222324799
290UbiquitinationLLTPLISKLSPYPSS
HHHHHHHHCCCCCCC		46.0922790023
292PhosphorylationTPLISKLSPYPSSPM
HHHHHHCCCCCCCCC		26.5626824392
294PhosphorylationLISKLSPYPSSPMRR
HHHHCCCCCCCCCCC		16.6326643407
296PhosphorylationSKLSPYPSSPMRRPQ
HHCCCCCCCCCCCCC		41.0325177544
297PhosphorylationKLSPYPSSPMRRPQS
HCCCCCCCCCCCCCC		20.4323527152
304PhosphorylationSPMRRPQSADAYMTR
CCCCCCCCHHHHHHC		30.6925521595
308PhosphorylationRPQSADAYMTRSLNP
CCCCHHHHHHCCCCH		10.2829899451
310PhosphorylationQSADAYMTRSLNPAL
CCHHHHHHCCCCHHH		12.39-
312PhosphorylationADAYMTRSLNPALDG
HHHHHHCCCCHHHCC		24.2725521595
321PhosphorylationNPALDGLTCGLTSHD
CHHHCCCCCCCCCCC		15.2822871156
332PhosphorylationTSHDKRISDLGNKTS
CCCCCCHHHCCCCCC		30.7122324799
338PhosphorylationISDLGNKTSPMSHSF
HHHCCCCCCCCCCCC		41.9029899451
339PhosphorylationSDLGNKTSPMSHSFA
HHCCCCCCCCCCCCC		21.8821183079
342PhosphorylationGNKTSPMSHSFANFH
CCCCCCCCCCCCCCC		21.2621082442
344PhosphorylationKTSPMSHSFANFHYP
CCCCCCCCCCCCCCC		20.8122817900
359PhosphorylationGVQNLSRSLMLENTE
CHHHHCHHHHCCCCC		18.1125521595
374PhosphorylationCHSIYEESPERSDTP
CCCCCCCCCCCCCCC		21.81-
378PhosphorylationYEESPERSDTPVEAQ
CCCCCCCCCCCCCCC		44.1429899451
380PhosphorylationESPERSDTPVEAQQP
CCCCCCCCCCCCCCC		30.4025521595
423PhosphorylationEKNELRDSTEQFQEY
HHHHHHHHHHHHHHH		27.6619060867
424PhosphorylationKNELRDSTEQFQEYY
HHHHHHHHHHHHHHH		37.7925293948
493PhosphorylationELNIGMDSLGNEVPV
CCCCCCCCCCCCCCC		29.3229899451
523PhosphorylationSSVTSFSTPPQDSSQ
CCCCCCCCCCCCCHH		36.66-
543PhosphorylationTANIHTSTPRNPGST
CCCCCCCCCCCCCCC		27.67-
620PhosphorylationVAFHPSGSLYAVGSN
EEECCCCCEEEEECC		23.6521183079
626PhosphorylationGSLYAVGSNSKTLRV
CCEEEEECCCCEEEE		31.1921183079
628PhosphorylationLYAVGSNSKTLRVCA
EEEEECCCCEEEEEE		28.8122817900
823PhosphorylationLATGQEDSSCMLYDI
EEECCCCCCCEEEEE		25.3728285833
824PhosphorylationATGQEDSSCMLYDIR
EECCCCCCCEEEEEC		18.8328285833
878UbiquitinationDLQGDLTKQLPLMVV
ECCCCHHHCCCEEEE		58.0722790023
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of WDR47_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of WDR47_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of WDR47_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of WDR47_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of WDR47_MOUSE

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry.";
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.;
J. Proteome Res. 7:5314-5326(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-312, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory