WDR3_MOUSE - dbPTM
WDR3_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID WDR3_MOUSE
UniProt AC Q8BHB4
Protein Name WD repeat-containing protein 3
Gene Name Wdr3
Organism Mus musculus (Mouse).
Sequence Length 942
Subcellular Localization Nucleus, nucleolus.
Protein Description
Protein Sequence MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGNKQEVTCLCPSPDGLHLAVGYEDGAIRIFSLLSGEGNITFNGHKAAVTSLKYDQLGGRLASGSKDTDVIIWDVINESGLYRLKGHKDAVTQALFLRERNLLVTSGKDTMVKWWDLDNQHCFKTMVGHRTEVWGLVLVSEEKRLITGAADSELRAWDIDYLQEIDDPEEPEPKKIKECPGIQDTPESEDSTLEADDEKSEDRILSCSKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLEVFCILSKAEVQKKMDKKLKKARKKARLNSANEEEDPETSVSMTLQDEILRVAKIKTSAKIKSFDLIHSPQGELKAVFLLQNNLVELYSLNASLPAPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMPCEYALCSFFVPGDRQVVIGTKTGNLQLYDLASGTLLETIAAHDGALWSMSLSPDQRGFVTGGADKAVKFWDFELVTDKNSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKVFYVDTLKFFLSLYGHKLPVLCMDISHDGALIATGSADRNVKIWGLDFGDCHRSLFAHDDSVMYLRFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSASHDKSLRLWERTREPLILEEEREMQREAEYEESVAKEDQPAVPGETQGDNYFTGKKTIETVKAAERIMEAIELHREETAKMKEHRAICKAAGKEVPLPVNPILMAHGNISPSAYVLETFKGIRSSELEEALLVLPFSYVPDVLTLFNEFIQTGLDVELLCRCLFFLLRIHFGQITSNQMLVPVIEKLKETTISKVRQVQDAIGFNMAGLDYLKRECEAKSEVMFFAEATSHLEEKKKKRKNRKRMILTLT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MGLTKQYLRYVASA
-CCCCHHHHHHHHHH		8.49-
246PhosphorylationECPGIQDTPESEDST
CCCCCCCCCCCCCCC		16.7525619855
249PhosphorylationGIQDTPESEDSTLEA
CCCCCCCCCCCCCCC		48.1628973931
252PhosphorylationDTPESEDSTLEADDE
CCCCCCCCCCCCCCC		30.7327087446
253PhosphorylationTPESEDSTLEADDEK
CCCCCCCCCCCCCCC		40.7227087446
261PhosphorylationLEADDEKSEDRILSC
CCCCCCCCHHHCHHC		42.5625619855
333PhosphorylationRKKARLNSANEEEDP
HHHHHHCCCCCCCCC		36.7425159016
342PhosphorylationNEEEDPETSVSMTLQ
CCCCCCCCCCEEEHH		39.5525159016
343PhosphorylationEEEDPETSVSMTLQD
CCCCCCCCCEEEHHH		15.5525159016
345PhosphorylationEDPETSVSMTLQDEI
CCCCCCCEEEHHHHH		13.0526745281
347PhosphorylationPETSVSMTLQDEILR
CCCCCEEEHHHHHHH		17.4826745281
419PhosphorylationGHRSDVRTLSFSSDN
CCHHHCEEEEECCCC		26.9722871156
436PhosphorylationVLSAAADSIKIWNRS
HHHHHHHHHEECCHH		22.5122871156
484PhosphorylationLQLYDLASGTLLETI
EEEEECCCCCCHHHH		39.34-
486PhosphorylationLYDLASGTLLETIAA
EEECCCCCCHHHHHH		26.19-
490PhosphorylationASGTLLETIAAHDGA
CCCCCHHHHHHCCCC		18.84-
725PhosphorylationREAEYEESVAKEDQP
HHHHHHHHHCCCCCC		18.55-
932AcetylationEEKKKKRKNRKRMIL
HHHHHHHHHCCCCEE		70.737923571
940PhosphorylationNRKRMILTLT-----
HCCCCEEEEC-----		19.8919737024
942PhosphorylationKRMILTLT-------
CCCEEEEC-------		31.1819737024
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of WDR3_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of WDR3_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of WDR3_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of WDR3_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of WDR3_MOUSE

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Related Literatures of Post-Translational Modification

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