WDR37_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: WDR37_MOUSE
• UniProt AC: Q8CBE3
• Protein Name: WD repeat-containing protein 37
• Gene Name: Wdr37
• Organism: Mus musculus (Mouse).
• Sequence Length: 496
• Protein Sequence: MPTESGSCSTARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIDTLNERLAGEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIGWNINIPALLQEK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	QAKQKRKSHSLSIRR HHHHHHHHCCCCEEC	23.49	22324799
22	Phosphorylation	KQKRKSHSLSIRRTN HHHHHHCCCCEECCC	30.79	22324799
24	Phosphorylation	KRKSHSLSIRRTNSS HHHHCCCCEECCCCC	19.64	26824392
28	Phosphorylation	HSLSIRRTNSSEQER CCCCEECCCCCHHHH	29.60	25266776
30	Phosphorylation	LSIRRTNSSEQERTG CCEECCCCCHHHHHC	34.34	26824392
31	Phosphorylation	SIRRTNSSEQERTGL CEECCCCCHHHHHCC	45.42	22324799
48	Phosphorylation	EMLEGQDSKLPSSVR HHHCCCCCCCCHHHH	28.36	28576409
112	Phosphorylation	GQLKTKASHSTSQLS CCCCCHHCCCHHHHH	21.37	20415495
114	Phosphorylation	LKTKASHSTSQLSQK CCCHHCCCHHHHHHH	27.53	29899451
115	Phosphorylation	KTKASHSTSQLSQKL CCHHCCCHHHHHHHH	18.31	20415495
116	Phosphorylation	TKASHSTSQLSQKLK CHHCCCHHHHHHHHH	31.94	20415495
119	Phosphorylation	SHSTSQLSQKLKTTY CCCHHHHHHHHHHHC	20.03	25266776
121	Ubiquitination	STSQLSQKLKTTYKA CHHHHHHHHHHHCHH	48.88	22790023
135	Phosphorylation	ASTSKIVSSFKTTTS HHHHHHHHCCCHHHH	33.27	29176673
136	Phosphorylation	STSKIVSSFKTTTSR HHHHHHHCCCHHHHH	21.62	25266776
138	Ubiquitination	SKIVSSFKTTTSRAI HHHHHCCCHHHHHHH	47.08	22790023
139	Phosphorylation	KIVSSFKTTTSRAIC HHHHCCCHHHHHHHH	33.04	29176673
165	O-linked_Glycosylation	GIWDVSVTRTQPIVL CCCEEEEEECCCEEE	22.09	55414609
254	Phosphorylation	GEDEIECSDKDEPDI CCCCEECCCCCCCCC	34.60	25521595

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of WDR37_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of WDR37_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of WDR37_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of WDR37_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.