dbPTM

WDR13_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	WDR13_MOUSE
UniProt AC	Q91V09
Protein Name	WD repeat-containing protein 13
Gene Name	Wdr13
Organism	Mus musculus (Mouse).
Sequence Length	485
Subcellular Localization	Nucleus.
Protein Description
Protein Sequence	MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQLLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSVAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIREIPDPDGAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGALQLKRSFPIEQSSHPVRSIFCPLMSFRQGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRREQK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Methylation	TPTFPQFRTQYIRRR CCCCHHHHHHHHHHH	18.70	54541897
27	Dimethylation	TPTFPQFRTQYIRRR CCCCHHHHHHHHHHH	18.70	-
35	Phosphorylation	TQYIRRRSQLLRENA HHHHHHHHHHHHHHH	24.30	29472430
66	Phosphorylation	GQLLGQRYGPLSEPG HHHHCCCCCCCCCCC	18.40	23737553
70	Phosphorylation	GQRYGPLSEPGSARA CCCCCCCCCCCCHHH	44.90	26824392
74	Phosphorylation	GPLSEPGSARAYSNS CCCCCCCCHHHHCCH	25.87	22324799
78	Phosphorylation	EPGSARAYSNSIVRS CCCCHHHHCCHHHHC	11.66	28066266
79	Phosphorylation	PGSARAYSNSIVRSS CCCHHHHCCHHHHCC	24.10	23527152
81	Phosphorylation	SARAYSNSIVRSSRT CHHHHCCHHHHCCCC	19.27	23684622
85	Phosphorylation	YSNSIVRSSRTTLDR HCCHHHHCCCCCHHC	17.18	29514104
86	Phosphorylation	SNSIVRSSRTTLDRM CCHHHHCCCCCHHCH	24.07	24759943
111	Phosphorylation	GARGHRRSVSRGSYQ HCCCCCCCCCCCCHH	25.13	27087446
113	Phosphorylation	RGHRRSVSRGSYQLQ CCCCCCCCCCCHHHH	31.97	27087446
114	Asymmetric dimethylarginine	GHRRSVSRGSYQLQA CCCCCCCCCCHHHHH	35.60	-
114	Methylation	GHRRSVSRGSYQLQA CCCCCCCCCCHHHHH	35.60	24129315
116	Phosphorylation	RRSVSRGSYQLQAQM CCCCCCCCHHHHHHH	14.48	27087446
117	Phosphorylation	RSVSRGSYQLQAQMN CCCCCCCHHHHHHHH	18.96	22324799
123	Oxidation	SYQLQAQMNRAVYED CHHHHHHHHHHHHCC	4.03	17242355
135	Phosphorylation	YEDRPPGSVVPTSVA HCCCCCCCCCCCHHH	26.22	29899451
140	O-linked_Glycosylation	PGSVVPTSVAEASRA CCCCCCCHHHHHHHH	17.17	22517741
267	Phosphorylation	GAELLCCTFQPVNNN CCEEEEEEEEEECCC	25.06	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of WDR13_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of WDR13_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of WDR13_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of WDR13_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of WDR13_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-116, AND MASSSPECTROMETRY.	17242355 [Abstract]