WDR13_HUMAN - dbPTM
WDR13_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID WDR13_HUMAN
UniProt AC Q9H1Z4
Protein Name WD repeat-containing protein 13
Gene Name WDR13
Organism Homo sapiens (Human).
Sequence Length 485
Subcellular Localization Nucleus .
Protein Description
Protein Sequence MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQLLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDHGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRREQK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
1 (in isoform 2)Acetylation-4.9522814378
35PhosphorylationTQYIRRRSQLLRENA
HHHHHHHHHHHHHHH		24.3023532336
66PhosphorylationGQLLGQRYGPLSEPG
HHHHCCCCCCCCCCC		18.4023403867
70PhosphorylationGQRYGPLSEPGSARA
CCCCCCCCCCCCHHH		44.9029255136
74PhosphorylationGPLSEPGSARAYSNS
CCCCCCCCHHHHCCH		25.8729255136
78PhosphorylationEPGSARAYSNSIVRS
CCCCHHHHCCHHHHC		11.6623403867
79PhosphorylationPGSARAYSNSIVRSS
CCCHHHHCCHHHHCC		24.1029255136
81PhosphorylationSARAYSNSIVRSSRT
CHHHHCCHHHHCCCC		19.2729255136
85PhosphorylationYSNSIVRSSRTTLDR
HCCHHHHCCCCCHHC		17.1824719451
89PhosphorylationIVRSSRTTLDRMEDF
HHHCCCCCHHCHHHC		26.0824719451
111PhosphorylationGARGHRRSVSRGSYQ
HCCCCCCCCCCCCHH		25.1326055452
113PhosphorylationRGHRRSVSRGSYQLQ
CCCCCCCCCCCHHHH		31.9722617229
114MethylationGHRRSVSRGSYQLQA
CCCCCCCCCCHHHHH		35.6024129315
114Asymmetric dimethylarginineGHRRSVSRGSYQLQA
CCCCCCCCCCHHHHH		35.60-
116PhosphorylationRRSVSRGSYQLQAQM
CCCCCCCCHHHHHHH		14.4821955146
117PhosphorylationRSVSRGSYQLQAQMN
CCCCCCCHHHHHHHH		18.9622617229
128PhosphorylationAQMNRAVYEDRPPGS
HHHHHHHHCCCCCCC		15.8921945579
135PhosphorylationYEDRPPGSVVPTSAA
HCCCCCCCCCCCCHH		26.2221945579
140O-linked_GlycosylationPGSVVPTSAAEASRA
CCCCCCCCHHHHHHH		21.2928657654
152PhosphorylationSRAMAGDTSLSENYA
HHHHCCCCCCCHHHH		30.5627251275
153PhosphorylationRAMAGDTSLSENYAF
HHHCCCCCCCHHHHH		34.3427251275
155PhosphorylationMAGDTSLSENYAFAG
HCCCCCCCHHHHHCC		24.4627251275
158PhosphorylationDTSLSENYAFAGMYH
CCCCCHHHHHCCHHH		10.0727251275
164PhosphorylationNYAFAGMYHVFDQHV
HHHHCCHHHHHHHCH		8.23-
202UbiquitinationGSISLCQLVPAPPTV
CCEEEEEECCCCHHH		4.9329967540
217PhosphorylationLRVLRGHTRGVSDFA
HHHHCCCCCCHHHHH		31.76-
288UbiquitinationAKHNVHVMNISTGKK
CCCCEEEEEECCCCE		1.9121987572
292PhosphorylationVHVMNISTGKKVKGG
EEEEEECCCCEECCC		49.5830576142
294UbiquitinationVMNISTGKKVKGGSS
EEEECCCCEECCCCC		55.2529967540
304UbiquitinationKGGSSKLTGRVLALS
CCCCCCCCCCEEEEE		27.0322817900
337PhosphorylationSFLFDMATGKLTKAK
HHHHHHHCCCCCCCE		28.3622210691
352PhosphorylationRLVVHEGSPVTSISA
EEEEECCCCCCEEEC		17.1424719451
358PhosphorylationGSPVTSISARSWVSR
CCCCCEEECCHHHCH		19.87-
380UbiquitinationLINACLNKLLLYRVV
HHHHHHHHHHHCEEE		27.8021987572
396UbiquitinationNEGTLQLKRSFPIEQ
CCCCEEEEEECCCCC		32.7922817900
417PhosphorylationSIFCPLMSFRQGACV
HCCCCHHCCCCCEEE		25.5924719451
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of WDR13_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of WDR13_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of WDR13_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of WDR13_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of WDR13_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle.";
Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.;
Mol. Cell 31:438-448(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-70, AND MASSSPECTROMETRY.

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