dbPTM

WBS14_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	WBS14_CAEEL
UniProt AC	P41846
Protein Name	Protein WBSCR14 homolog
Gene Name	mml-1
Organism	Caenorhabditis elegans.
Sequence Length	1009
Subcellular Localization	Nucleus .
Protein Description	Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity)..
Protein Sequence	MSRGQIIHSGHFMCSNPHDDLVQDEDEEDVEVDVVEDDDKSMEASSSVHHKNKALDEKPVTFYKFGVGKTQSIAIDVSLNKLNKCIKVAYNKMTTPKWKDFKGLRLHWKQRVRLNNVIWRAYYIEFRKKQPEKPKKPFCYFAVPDDDTTHQKIEGSIVEGMYWKRKMEGVCAQYKRWRIRSKHNLVTDKGGMVATCSSTSVSSMTGELKRKRKHTVPKETIESKLRSYEPPVKLQRSQTPKHTISDEFAWDFDDLDNVFTDDFLNSLSEPYMFPDPRDVYSGNNADIMQPGLLPLQPTIEDIMMSLGDDMPDSPPFHNDRDTMRTPTNDQPSISAQQIPQMRRSASSSASLHQMQVAQAQAQSISQISQPSQQLQHQIQIQQPVAARPHEFMASSIMMDYRLMPTRQSSAITSQMLMLSQSASTLSSQPQYATSTHYSTNNSFLPIRNTMTNQHHLGHTSQHSPWNKQQQSNFLVSLPHQSHVERILNNQPPLVPPPSRSNLLPTQNDPYLPQFLQSTQPTPQPQSHDPMMAPSRSWWLDSPLTASVQSPLSVATPLPLANQTGPQTPLGQLIGSADNGFLFGGNNTPGGFKMSGTTSGVPTLSQRLEQPPISRTSTIFGNVENKPERIFTSLTSQNTPTPSPLDISSLSRLRTSSLNESWKMSHIVEGSPTYQAFAASVTTKPSILESPSTSGDISGPASVPVQASQHPPKIITPPSASSKRKEQEAAMAPLVNRQQSCDVNLLNGKMAVKVEEKSGRHYLPTTPTELKEVTKEEPLLMSAPSSVKSMRRQAPDSTLHPEERKRILHLHAEQNRRSALKDGFDQLMDIIPDLYSGGVKPTNAVVLAKSADHIRRLQAEKWDKTQKIDEAKAKIEKLNQKITSLQSNLPQSSAPSSSSQVDSKTSLETFFDRYVKEGAKKNWRFWVMSQMLKPICVTQTNSFASSVAGDSSSRNEVAASCSDWLNKNWKATELRPLASTLLVSLATNSSILAEPDTLPDYVMQQLKNPF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
715	Phosphorylation	QHPPKIITPPSASSK CCCCCCCCCCCCCCH	32.40	28854356
739	Phosphorylation	PLVNRQQSCDVNLLN HHHCCHHCCCEEECC	12.16	19530675
765	Phosphorylation	GRHYLPTTPTELKEV CCCCCCCCCHHHHHC	26.69	28854356
784	Phosphorylation	PLLMSAPSSVKSMRR CCCCCCCHHHHHHHH	47.70	28854356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of WBS14_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of WBS14_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of WBS14_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of WBS14_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of WBS14_CAEEL

Related Literatures of Post-Translational Modification