WBP1L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: WBP1L_HUMAN
• UniProt AC: Q9NX94
• Protein Name: WW domain binding protein 1-like
• Gene Name: WBP1L
• Organism: Homo sapiens (Human).
• Sequence Length: 342
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MPFLLGLRQDKEACVGTNNQSYICDTGHCCGQSQCCNYYYELWWFWLVWTIIIILSCCCVCHHRRAKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSAFQLQQQQLLPPQCGPAGGSPPGIDPTRGSQGAQSSPLSEPSRSSTRPPSIADPDPSDLPVDRAATKAPGMEPSGSVAGLGELDPGAFLDKDAECREELLKDDSSEHGAPDSKEKTPGRHRRFTGDSGIEVCVCNRGHHDDDLKEFNTLIDDALDGPLDFCDSCHVRPPGDEEEGLCQSSEEQAREPGHPHLPRPPACLLLNTINEQDSPNSQSSSSPS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
90	Phosphorylation	AYREAHNYSALPFYF HHHHHCCCCCCCCCC	5.85	28152594
91	Phosphorylation	YREAHNYSALPFYFR HHHHCCCCCCCCCCC	28.75	28152594
96	Phosphorylation	NYSALPFYFRFLPNY CCCCCCCCCCCCCCC	7.60	-
107	Ubiquitination	LPNYLLPPYEEVVNR CCCCCCCCHHHHCCC	49.49	22817900
158	Phosphorylation	RGSQGAQSSPLSEPS CCCCCCCCCCCCCCC	33.13	25262027
159	Phosphorylation	GSQGAQSSPLSEPSR CCCCCCCCCCCCCCC	20.13	27470641
162	Phosphorylation	GAQSSPLSEPSRSST CCCCCCCCCCCCCCC	51.34	25262027
165	Phosphorylation	SSPLSEPSRSSTRPP CCCCCCCCCCCCCCC	40.52	26852163
167	Phosphorylation	PLSEPSRSSTRPPSI CCCCCCCCCCCCCCC	40.16	30266825
168	Phosphorylation	LSEPSRSSTRPPSIA CCCCCCCCCCCCCCC	27.59	30266825
169	Phosphorylation	SEPSRSSTRPPSIAD CCCCCCCCCCCCCCC	48.74	30266825
173	Phosphorylation	RSSTRPPSIADPDPS CCCCCCCCCCCCCHH	32.84	23401153
180	Phosphorylation	SIADPDPSDLPVDRA CCCCCCHHHCCCCHH	60.19	30266825
189 (in isoform 2)	Phosphorylation	-	27.10	27251275
189	Phosphorylation	LPVDRAATKAPGMEP CCCCHHHHCCCCCCC	27.10	22210691
190	Ubiquitination	PVDRAATKAPGMEPS CCCHHHHCCCCCCCC	48.10	22817900
194 (in isoform 2)	Phosphorylation	-	7.15	24719451
197	Phosphorylation	KAPGMEPSGSVAGLG CCCCCCCCCCCCCCC	30.32	29514088
199	Phosphorylation	PGMEPSGSVAGLGEL CCCCCCCCCCCCCCC	17.09	26074081
202	Ubiquitination	EPSGSVAGLGELDPG CCCCCCCCCCCCCCC	31.87	22817900
211	Ubiquitination	GELDPGAFLDKDAEC CCCCCCCCCCCCHHH	12.89	33845483
220 (in isoform 2)	Phosphorylation	-	65.73	27251275
227	Phosphorylation	EELLKDDSSEHGAPD HHHHHCCCHHCCCCC	48.00	26657352
228	Phosphorylation	ELLKDDSSEHGAPDS HHHHCCCHHCCCCCC	40.38	25849741
235	Phosphorylation	SEHGAPDSKEKTPGR HHCCCCCCCCCCCCC	41.47	29255136
236	Ubiquitination	EHGAPDSKEKTPGRH HCCCCCCCCCCCCCC	71.28	33845483
247	Phosphorylation	PGRHRRFTGDSGIEV CCCCCCCCCCCCCEE	37.96	30576142
248 (in isoform 2)	Phosphorylation	-	25.11	24719451
250	Phosphorylation	HRRFTGDSGIEVCVC CCCCCCCCCCEEEEE	42.91	30576142
257	Ubiquitination	SGIEVCVCNRGHHDD CCCEEEEECCCCCCC	2.13	33845483
268 (in isoform 2)	Phosphorylation	-	51.96	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of WBP1L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of WBP1L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of WBP1L_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of WBP1L_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.