VWA7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VWA7_HUMAN
• UniProt AC: Q9Y334
• Protein Name: von Willebrand factor A domain-containing protein 7
• Gene Name: VWA7
• Organism: Homo sapiens (Human).
• Sequence Length: 891
• Subcellular Localization: Secreted .
• Protein Sequence: MLPTEVPQSHPGPSALLLLQLLLPPTSAFFPNIWSLLAAPGSITHQDLTEEAALNVTLQLFLEQPPPGRPPLRLEDFLGRTLLADDLFAAYFGPGSSRRFRAALGEVSRANAAQDFLPTSRNDPDLHFDAERLGQGRARLVGALRETVVAARALDHTLARQRLGAALHALQDFYSHSNWVELGEQQPHPHLLWPRQELQNLAQVADPTCSDCEELSCPRNWLGFTLLTSGYFGTHPPKPPGKCSHGGHFDRSSSQPPRGGINKDSTSPGFSPHHMLHLQAAKLALLASIQAFSLLRSRLGDRDFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARHLVEQRRGSPMEPVHYVLVPFHDPGFGPVFTTSDPDSFWQQLNEIHALGGGDEPEMCLSALQLALLHTPPLSDIFVFTDASPKDAFLTNQVESLTQERRCRVTFLVTEDTSRVQGRARREILSPLRFEPYKAVALASGGEVIFTKDQHIRDVAAIVGESMAALVTLPLDPPVVVPGQPLVFSVDGLLQKITVRIHGDISSFWIKNPAGVSQGQEEGGGPLGHTRRFGQFWMVTMDDPPQTGTWEIQVTAEDTPGVRVQAQTSLDFLFHFGIPMEDGPHPGLYPLTQPVAGLQTQLLVEVTGLGSRANPGDPQPHFSHVILRGVPEGAELGQVPLEPVGPPERGLLAASLSPTLLSTPRPFSLELIGQDAAGRRLHRAAPQPSTVVPVLLELSGPSGFLAPGSKVPLSLRIASFSGPQDLDLRTFVNPSFSLTSNLSRAHLELNESAWGRLWLEVPDSAAPDSVVMVTVTAGGREANPVPPTHAFLRLLVSAPAPQDRHTTPTGSSDPILTTATPAFSPFTLVTQGRAGAGLAAGSPWWGTVGGVLLLLGLASW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
55	N-linked_Glycosylation	LTEEAALNVTLQLFL CCHHHHHHHEHHHHH	21.72	UniProtKB CARBOHYD
225	Phosphorylation	PRNWLGFTLLTSGYF CCCHHCEEEECCCCC	21.04	25072903
228	Phosphorylation	WLGFTLLTSGYFGTH HHCEEEECCCCCCCC	24.18	25072903
229	Phosphorylation	LGFTLLTSGYFGTHP HCEEEECCCCCCCCC	31.31	25072903
231	Phosphorylation	FTLLTSGYFGTHPPK EEEECCCCCCCCCCC	9.90	25072903
234	Phosphorylation	LTSGYFGTHPPKPPG ECCCCCCCCCCCCCC	22.70	25072903
288	Phosphorylation	AKLALLASIQAFSLL HHHHHHHHHHHHHHH	18.40	-
461	Phosphorylation	RARREILSPLRFEPY HHHHHHCCCCCCCCC	27.78	28188228
475	Phosphorylation	YKAVALASGGEVIFT CEEEEEEECCEEEEE	48.45	-
482	Phosphorylation	SGGEVIFTKDQHIRD ECCEEEEECCCHHHH	23.69	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VWA7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VWA7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VWA7_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of VWA7_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.