| UniProt ID | VSTM1_HUMAN | |
|---|---|---|
| UniProt AC | Q6UX27 | |
| Protein Name | V-set and transmembrane domain-containing protein 1 | |
| Gene Name | VSTM1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 236 | |
| Subcellular Localization |
Isoform 1: Membrane Single-pass membrane protein . Isoform 2: Secreted . |
|
| Protein Description | Isoform 2: Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17).; Isoform 1: Inhibitory immune receptor involved in the regulation of phagocytes.. | |
| Protein Sequence | MTAEFLSLLCLGLCLGYEDEKKNEKPPKPSLHAWPSSVVEAESNVTLKCQAHSQNVTFVLRKVNDSGYKQEQSSAENEAEFPFTDLKPKDAGRYFCAYKTTASHEWSESSEHLQLVVTDKHDELEAPSMKTDTRTIFVAIFSCISILLLFLSVFIIYRCSQHSSSSEESTKRTSHSKLPEQEAAEADLSNMERVSLSTADPQGVTYAELSTSALSEAASDTTQEPPGSHEYAALKV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 43 | Phosphorylation | SSVVEAESNVTLKCQ CCCEEEECCEEEEEE | 43.58 | 22210691 | |
| 44 | N-linked_Glycosylation | SVVEAESNVTLKCQA CCEEEECCEEEEEEE | 23.46 | UniProtKB CARBOHYD | |
| 55 | N-linked_Glycosylation | KCQAHSQNVTFVLRK EEEEECCEEEEEEEE | 37.50 | UniProtKB CARBOHYD | |
| 173 | Phosphorylation | SEESTKRTSHSKLPE CHHHHHHCCCCCCCH | 32.14 | 26434552 | |
| 210 | Phosphorylation | GVTYAELSTSALSEA CCCHHEECHHHHHHH | 16.30 | 22468782 | |
| 221 | Phosphorylation | LSEAASDTTQEPPGS HHHHHCCCCCCCCCC | 28.08 | 22468782 | |
| 228 | Phosphorylation | TTQEPPGSHEYAALK CCCCCCCCCCCEEEE | 20.94 | 22468782 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VSTM1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VSTM1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VSTM1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of VSTM1_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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