VS10L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VS10L_HUMAN
• UniProt AC: Q86VR7
• Protein Name: V-set and immunoglobulin domain-containing protein 10-like
• Gene Name: VSIG10L
• Organism: Homo sapiens (Human).
• Sequence Length: 867
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Sequence: MDNPQALPLFLLLASLVGILTLRASSGLQQTNFSSAFSSDSKSSSQGLGVEVPSIKPPSWKVPDQFLDSKASAGISDSSWFPEALSSNMSGSFWSNVSAEGQDLSPVSPFSETPGSEVFPDISDPQVPAKDPKPSFTVKTPASNISTQVSHTKLSVEAPDSKFSPDDMDLKLSAQSPESKFSAETHSAASFPQQVGGPLAVLVGTTIRLPLVPIPNPGPPTSLVVWRRGSKVLAAGGLGPGAPLISLDPAHRDHLRFDQARGVLELASAQLDDAGVYTAEVIRAGVSQQTHEFTVGVYEPLPQLSVQPKAPETEEGAAELRLRCLGWGPGRGELSWSRDGRALEAAESEGAETPRMRSEGDQLLIVRPVRSDHARYTCRVRSPFGHREAAADVSVFYGPDPPTITVSSDRDAAPARFVTAGSNVTLRCAAASRPPADITWSLADPAEAAVPAGSRLLLPAVGPGHAGTYACLAANPRTGRRRRSLLNLTVADLPPGAPQCSVEGGPGDRSLRFRCSWPGGAPAASLQFQGLPEGIRAGPVSSVLLAAVPAHPRLSGVPITCLARHLVATRTCTVTPEAPREVLLHPLVAETRLGEAEVALEASGCPPPSRASWAREGRPLAPGGGSRLRLSQDGRKLHIGNFSLDWDLGNYSVLCSGALGAGGDQITLIGPSISSWRLQRARDAAVLTWDVERGALISSFEIQAWPDGPALGRTSTYRDWVSLLILGPQERSAVVPLPPRNPGTWTFRILPILGGQPGTPSQSRVYRAGPTLSHGAIAGIVLGSLLGLALLAVLLLLCICCLCRFRGKTPEKKKHPSTLVPVVTPSEKKMHSVTPVEISWPLDLKVPLEDHSSTRAYQAQTPVQLSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	N-linked_Glycosylation	SSGLQQTNFSSAFSS CCCCCCCCCCHHCCC	30.39	UniProtKB CARBOHYD
86	Phosphorylation	SWFPEALSSNMSGSF CCCHHHHHCCCCCCC	27.06	22468782
88	N-linked_Glycosylation	FPEALSSNMSGSFWS CHHHHHCCCCCCCCC	25.84	UniProtKB CARBOHYD
92	Phosphorylation	LSSNMSGSFWSNVSA HHCCCCCCCCCCCCC	19.08	22468782
95	Phosphorylation	NMSGSFWSNVSAEGQ CCCCCCCCCCCCCCC	25.91	22468782
96	N-linked_Glycosylation	MSGSFWSNVSAEGQD CCCCCCCCCCCCCCC	23.51	UniProtKB CARBOHYD
144	N-linked_Glycosylation	TVKTPASNISTQVSH EEECCCCCCCCCEEE	34.04	UniProtKB CARBOHYD
164	Phosphorylation	EAPDSKFSPDDMDLK ECCCCCCCCCCCCEE	31.02	28270605
173	Phosphorylation	DDMDLKLSAQSPESK CCCCEEHHCCCCCCC	23.75	28270605
182	Phosphorylation	QSPESKFSAETHSAA CCCCCCCCCCCCCCC	29.00	-
305	O-linked_Glycosylation	YEPLPQLSVQPKAPE ECCCCCCCCCCCCCC	17.29	29237092
397	Phosphorylation	AADVSVFYGPDPPTI CCEEEEEECCCCCCE	26.12	30576142
403	Phosphorylation	FYGPDPPTITVSSDR EECCCCCCEEECCCC	34.37	30576142
419	Phosphorylation	AAPARFVTAGSNVTL CCCCEEEECCCCEEE	23.69	24114839
423	N-linked_Glycosylation	RFVTAGSNVTLRCAA EEEECCCCEEEEEEC	29.85	UniProtKB CARBOHYD
487	N-linked_Glycosylation	RRRRSLLNLTVADLP CCCHHHHCEEECCCC	38.67	UniProtKB CARBOHYD
571	O-linked_Glycosylation	RHLVATRTCTVTPEA HHHEEECCCCCCCCC	14.26	29237092
603	Phosphorylation	AEVALEASGCPPPSR CCHHHHHCCCCCCCH	31.39	-
609	Phosphorylation	ASGCPPPSRASWARE HCCCCCCCHHHHHHC	46.37	-
641	N-linked_Glycosylation	GRKLHIGNFSLDWDL CCEEEECEEEECCCC	23.80	UniProtKB CARBOHYD
650	N-linked_Glycosylation	SLDWDLGNYSVLCSG EECCCCCCCEEEECC	32.95	UniProtKB CARBOHYD
732	Phosphorylation	ILGPQERSAVVPLPP EECCCCCCEEECCCC	25.35	22210691
746	Phosphorylation	PRNPGTWTFRILPIL CCCCCCEEEEEEEEC	11.68	22210691
759	Phosphorylation	ILGGQPGTPSQSRVY ECCCCCCCCCCCCCC	26.84	22210691
817	Phosphorylation	PEKKKHPSTLVPVVT CCCCCCCCCEEEEEC	33.81	29514088
818	Phosphorylation	EKKKHPSTLVPVVTP CCCCCCCCEEEEECC	35.90	29514088
824	Phosphorylation	STLVPVVTPSEKKMH CCEEEEECCCCCCCC	22.72	29514088
826	Phosphorylation	LVPVVTPSEKKMHSV EEEEECCCCCCCCCC	53.32	29514088
828	Ubiquitination	PVVTPSEKKMHSVTP EEECCCCCCCCCCCC	60.79	33845483
832	Phosphorylation	PSEKKMHSVTPVEIS CCCCCCCCCCCEEEE	24.96	24732914
834	Phosphorylation	EKKMHSVTPVEISWP CCCCCCCCCEEEECC	25.32	24732914
839	Phosphorylation	SVTPVEISWPLDLKV CCCCEEEECCCCEEC	14.77	24732914
854 (in isoform 2)	Phosphorylation	-	23.49	28985074
857 (in isoform 2)	Phosphorylation	-	10.90	28985074
863 (in isoform 2)	Phosphorylation	-	11.53	28985074
872 (in isoform 2)	Phosphorylation	-		25690035

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VS10L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VS10L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VS10L_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of VS10L_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.