dbPTM

VRTN_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VRTN_MOUSE
UniProt AC	Q3SYK4
Protein Name	Vertnin
Gene Name	Vrtn
Organism	Mus musculus (Mouse).
Sequence Length	740
Subcellular Localization
Protein Description
Protein Sequence	MTSRDQLVQQVLRDLQEAVESEGLEGLIGAALEAKQVLSSFTLPICQKGGPGAQVLEVDSVALSLYPEDAPRNMLPLVCKGEGSLLFEATSLLLWGHTGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLCSEESPEMTNLSFATLEAIFDADVKATCFPTSFSNVWHLYALASILECNIYSIYPMRNIKIRPYFNRVIMPRCSTHVTSMLHIMWAGQPLTSHLFRHQYFAPVVGLEEVEADCTASLNPVPPNLGPLLPPAKTLELLNREPGLSYSHLCDRISITKSTFYRWRRQTQEHRQKVATRFSAKHFLQDSFHRGGFVPLQQFLQRFPEISRSTYYAWKHELLGSGANSALGPATPSREALAVPEVERPPGKKAAEEVGCSSLAAAMLSPPSMILMQRAKSFLEYCISLNKLVPYRCFKCRFPGISRSTYYNWRRKALRRTPSFKLSQAAFETAESLQPTDVGKETPFSLKREAGEEETGKAGSGAPLTSRGLISPKMPLSRWQRRLRRAARKQVLNGHLPFCRFRLRYPSLLPSTFWVWKSLSRRSPGMQIPSLSQRRQKPQGRQKPEGRQKPEEQQKPEGRQKPEGRQKPVEPQAMEADQNVPAMVVPPAETLPVATSPEDVPGGPSREGNIIQEAAMTQSQPHSGSLPSQTLAEAPGGSDGQVLVMDMLTTTRFKAQAKLFLQKRFQSKTFPSYKEFQALFPLTARSTYYMWKRALYEGLTLIDG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
270	Phosphorylation	PLLPPAKTLELLNRE CCCCCHHHHHHHHCC	27.80	27180971
559	Phosphorylation	WKSLSRRSPGMQIPS HHHCCCCCCCCCCCC	25.37	26643407
566	Phosphorylation	SPGMQIPSLSQRRQK CCCCCCCCHHHHCCC	42.13	26643407
568	Phosphorylation	GMQIPSLSQRRQKPQ CCCCCCHHHHCCCCC	26.44	26643407

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VRTN_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VRTN_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VRTN_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of VRTN_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VRTN_MOUSE

Related Literatures of Post-Translational Modification