VPS24_SCHPO - dbPTM
VPS24_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID VPS24_SCHPO
UniProt AC O14296
Protein Name Vacuolar protein sorting-associated protein 24
Gene Name vps24
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 231
Subcellular Localization Endosome membrane
Peripheral membrane protein. Endomembrane system
Peripheral membrane protein.
Protein Description Class E VPS protein implicated in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. The lumenal sequestrated membrane proteins will be targeted into the vacuole after fusion of the endosome with the vacuole..
Protein Sequence MQTVRSYFFGPTPQEQNRKWQSIIRKEQRQLDRQVYHLKAGRKKAEVQLKQLAKQSDITNMRILAKEIARANRHGKRLAESKALLGSLSLQLNDQMAMLKIQGTMQSSTKIMQDVSSLIRLPQLSETMRNLSMELTKAGVLEEMRDEMFLPVEDDEELMDLADEDEEVQEILTKYNVIPAPSEKAADAATHREQSLKQALPSLSNGIAKDSTEIDEEQLLDIRDKLDALKS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MQTVRSYFFG
-----CCCCHHHHCC
19.3124763107
190PhosphorylationEKAADAATHREQSLK
HHHHHHHHHHHHHHH
24.1621712547
195PhosphorylationAATHREQSLKQALPS
HHHHHHHHHHHHHHH
32.5524763107
202PhosphorylationSLKQALPSLSNGIAK
HHHHHHHHHHCCCCC
45.3321712547
204PhosphorylationKQALPSLSNGIAKDS
HHHHHHHHCCCCCCC
37.0321712547
211PhosphorylationSNGIAKDSTEIDEEQ
HCCCCCCCCCCCHHH
27.5124763107
212PhosphorylationNGIAKDSTEIDEEQL
CCCCCCCCCCCHHHH
47.2829996109
231PhosphorylationDKLDALKS-------
HHHHHHHC-------
46.4325720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of VPS24_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of VPS24_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of VPS24_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of VPS24_SCHPO !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of VPS24_SCHPO

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Related Literatures of Post-Translational Modification

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