VP9D1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VP9D1_MOUSE
• UniProt AC: Q8C190
• Protein Name: VPS9 domain-containing protein 1
• Gene Name: Vps9d1
• Organism: Mus musculus (Mouse).
• Sequence Length: 649
• Protein Sequence: MAAAAGDGGAKPLQSAMKLANKAIELDTGNRPREAYVEYLRSIHYISQVLLEDVENTTEAGETVPPETSKMLKLAEQCLERAQSTATKLGRICLKPAVPAAPPTPLPTSRHRRVCSDEGGKLSPFLPPEIFQKLQVAESQNSKKELTPLEKASLQNQKLRATYEARMARLDPSQAMQKTSLTLSLQRQMMENLVIAKAREETLQRKMEERRLRLQEAANRRFCSQVALTPEEREQRALYAAILEYEQDHDWPKHWRAKLKRSPGDLSLVTSLLSHLLSLPDHPISQLLKKLQCAVYSALYPIVSRAATSAAPAPGSCSLPPEANGLLAPGSRRLRSSQSLYCMLSPSEPSAAPRVLDGPPPTPSVPTLHSGPLDREADGSPAGPSSPLVDALSHLPDKDSSFEDLEQFLAMSEPQTPGAKREPLLECLKSTVKDIHNAIDRLLSLTLLAFESLNTATSKDRCLACIEEPFFSPLWPLLLALYRSVHRTREAAVSRSMELYRNAPPTALGIPTKLLPRVPEAQASTYPYCTAAQELGLLVLESCPQKKLECIVRTLRVICICAEDYCRAQEARPEGESQPPAAAIGADDLLPILSFVVLRSGLPQLVSECAALEEFTHEGYLIGEEGYCLTSLQSALSYVELLSRGRLDK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Acetylation	SAMKLANKAIELDTG HHHHHHHHCCCCCCC		7625353
88	Acetylation	RAQSTATKLGRICLK HHHHHHHHHHHHHCC		2383505
116	Phosphorylation	SRHRRVCSDEGGKLS CCCCCCCCCCCCCCC		26824392
123	Phosphorylation	SDEGGKLSPFLPPEI CCCCCCCCCCCCHHH		25293948
179	Phosphorylation	PSQAMQKTSLTLSLQ HHHHHHHHHHHHHHH		28059163
180	Phosphorylation	SQAMQKTSLTLSLQR HHHHHHHHHHHHHHH		28059163
336	Phosphorylation	PGSRRLRSSQSLYCM CCCHHCCCCCCEEEE		26643407
337	Phosphorylation	GSRRLRSSQSLYCML CCHHCCCCCCEEEEE		26643407
339	Phosphorylation	RRLRSSQSLYCMLSP HHCCCCCCEEEEECC		24719451
380	Phosphorylation	LDREADGSPAGPSSP CCCCCCCCCCCCCCH		25195567
385	Phosphorylation	DGSPAGPSSPLVDAL CCCCCCCCCHHHHHH		26060331
386	Phosphorylation	GSPAGPSSPLVDALS CCCCCCCCHHHHHHH		26824392
430	Phosphorylation	PLLECLKSTVKDIHN HHHHHHHHHHHHHHH		28418008
431	Phosphorylation	LLECLKSTVKDIHNA HHHHHHHHHHHHHHH		28418008
506	Phosphorylation	LYRNAPPTALGIPTK HHHCCCCCCCCCCCC		25159016

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VP9D1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VP9D1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VP9D1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of VP9D1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.