VP9D1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VP9D1_HUMAN
• UniProt AC: Q9Y2B5
• Protein Name: VPS9 domain-containing protein 1
• Gene Name: VPS9D1
• Organism: Homo sapiens (Human).
• Sequence Length: 631
• Protein Sequence: MAAAAGDGTVKPLQSAMKLANGAIELDTGNRPREAYTEYLRSIHYISQVLLEEVETTKEAGETVPPDTSKMLKLAQQCLERAQSTAAKLGKTRLKPTMPAAAPIPQPAGRHRRVYSDEGGKLSPFLPPEIFQKLQGAESQSCKKELTPLEEASLQNQKLKAAYEARMARLDPSQAMQKTSLTLSLQRQMMENLVIAKAREETLQRKMEERRLRLQEAANRRFCSQVALTPEEREQRALYAAILEYEQDHDWPKHWKAKLKRNPGDLSLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPVGSPSPLGDTASGLPDKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAVEEIHNAVDRLLSLTLLAFEGLNTAASKDRCLACIEEPFFSPLWPLLLALYRSVHRAREAALSRSMELYRNAPPTAIGIPTKLLPQNPEAKGATGYPYCAAAQELGLLVLESCPQKKLECIVRTLRIICVCAEDYCPTPEATPQAGPPPIAAAAIGADDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYVELLPRGGLAK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
57	Phosphorylation	LLEEVETTKEAGETV HHHHHHHHHHCCCCC		-
63	Phosphorylation	TTKEAGETVPPDTSK HHHHCCCCCCCCHHH		29083192
68	Phosphorylation	GETVPPDTSKMLKLA CCCCCCCHHHHHHHH		29083192
69	Phosphorylation	ETVPPDTSKMLKLAQ CCCCCCHHHHHHHHH		29083192
115	Phosphorylation	AGRHRRVYSDEGGKL CCCCCEEEECCCCCC		26699800
116	Phosphorylation	GRHRRVYSDEGGKLS CCCCEEEECCCCCCC		21815630
123	Phosphorylation	SDEGGKLSPFLPPEI ECCCCCCCCCCCHHH		23312004
144	Ubiquitination	AESQSCKKELTPLEE CCCCHHCCCCCHHHH		29967540
158	Ubiquitination	EASLQNQKLKAAYEA HHHHHHHHHHHHHHH		29967540
179	Phosphorylation	PSQAMQKTSLTLSLQ HHHHHHHHHHHHHHH		26029660
180	Phosphorylation	SQAMQKTSLTLSLQR HHHHHHHHHHHHHHH		26029660
184	Phosphorylation	QKTSLTLSLQRQMME HHHHHHHHHHHHHHH		24719451
317	Phosphorylation	APGCCPPTPNPGSRR CCCCCCCCCCCCCCC		29759185
328	Phosphorylation	GSRRLRPSQSLHCML CCCCCCCCCCEEEEC		23312004
330	Phosphorylation	RRLRPSQSLHCMLSP CCCCCCCCEEEECCC		23312004
336	Phosphorylation	QSLHCMLSPPEPSAA CCEEEECCCCCCCCC		23312004
341	Phosphorylation	MLSPPEPSAAPRPQD ECCCCCCCCCCCCCC		23312004
362	Phosphorylation	LQPGPVGSPSPLGDT CCCCCCCCCCCCCCC		-
378	Phosphorylation	SGLPDKDSSFEDLEQ CCCCCCCCCHHHHHH		22199227
379	Phosphorylation	GLPDKDSSFEDLEQF CCCCCCCCHHHHHHH		22199227
476	Phosphorylation	REAALSRSMELYRNA HHHHHHHHHHHHHCC		26657352
480	Phosphorylation	LSRSMELYRNAPPTA HHHHHHHHHCCCCCC		26657352

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VP9D1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VP9D1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VP9D1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of VP9D1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.