VP35B_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VP35B_ARATH
• UniProt AC: F4I0P8
• Protein Name: Vacuolar protein sorting-associated protein 35B
• Gene Name: VPS35B
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 790
• Subcellular Localization: Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Prevacuolar compartment membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side.
• Protein Description: Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. Also involved in the efficient sorting of seed storage proteins globulin 12S and albumin 2S. The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane..
• Protein Sequence: MRTLAGVEDEDKWLAEGIAGIQHNAFFMHRALDANNLREVLKYSALMLSELRTSKLSPQKYYDLYMRAFDQLRQLEIFFKDESRHGLPVVDLYELVQHAGNILPRMYLLCTVGSVYIKSKQAPSKDVLKDLVEMCRGVQHPIRGLFLRSYLAQVSRDKLPEIGSDYEGDANTVMDAVEFVLQNFTEMNKLWVRIQHQGPGTVREKQEKERNELRDLVGKNLHVLGQIEGVDLEMYKETVLPRVLEQVVNCKDKLAQYYLMECIIQVFPDEYHLQTLETLLAACTQLMPTVDTKIVLTQLMDRLSNYAASSPDVLHEFLQVEAFAKLSNAIGKVIDTQLEMPIVGAMTLFVSLLTFTLRVHPDRLDYVDQVLGACVVKLSSVPKLEDARAMKQVVALLSAPLEKYSDIVTALTLSNYPRVMDHLDDGTNKVMAMLIIQSIMKTDSCISTADKVEVLFELIKGLIKDLDETNAEELDEEDFQEEQNSVARLIHMLDNEEPEEMLKIICVVRRHLMTGGPRRLPFTVPPLVFSAVRLVRQLESQGGDIAGEDSATPRKIFQILNQTIEVLTSVPCPELALRLYLQCAEAASDCDLEPVAYEFFTQAFMLYEEEIADSKAQVTAIHLIVGTLQRINVFGVENRDTLTHKATGYSARLLKKPDQCRAVYACSHLFWVDDPDGIKDGERVLLCLRRALRIANAAQQMASATRGSSGPVTLFVEILNKYIYFFEKGNPHITPSDIQSLIELINNEMQSDNGNTTIHSDPFFTSTLRYIKFIKQKGGLMGEKYDPIKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of VP35B_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VP35B_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VP35B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VP35B_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VPS29_ARATH	MAG1	physical	18222962
VP26A_ARATH	VPS26A	physical	25681156
VP26B_ARATH	VPS26B	physical	25681156
VPS29_ARATH	MAG1	physical	25681156

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.